阜阳市儿童手足口病危险因素配对病例对照研究  

A paired case-control study on influencing factors of hand,foot and mouth disease among children in Fuyang City

作　　者：孙辉[1] SUN Hui(School of Medicine and Nursing,Fuyang Institute of Technology,Fuyang 236031,China)

机构地区：[1]阜阳职业技术学院医学护理学院,安徽阜阳236031

出　　处：《包头医学院学报》2022年第8期52-55,共4页Journal of Baotou Medical College

基　　金：安徽高校自然科学研究重点项目(NO.KJ2020A0947)。

摘　　要：目的:研究阜阳市儿童手足口病发病的危险因素。方法:通过中国“传染病报告信息管理系统”,采用多级抽样的方法从2个项目县共8个乡镇(社区)中调取2019年1月1日-2019年12月31日登记报告的年龄≤5岁手足口病患儿197例;同时,每调取1个病例,选择与该病例居住在同一村庄(小区)、年龄相差≤6个月的未患手足口病儿童作为对照。采用条件Logistic回归分析方法对手足口病的发病危险因素进行分析。结果:单因素条件Logistic回归分析显示监护人文化程度、监护人职业、儿童平时身体健康状况、监护人喂孩子前洗手和预防接种情况可能与儿童手足口病发病有关。多因素条件Logistic回归分析显示监护人文化程度、监护人职业、儿童平时身体健康状况和预防接种情况是手足口病发病的危险因素。结论:应加强手足口病防治知识的宣传教育,提高不同职业儿童监护人防控手足口病的能力;同时注重儿童体育活动和提高儿童疫苗接种率,增强儿童对手足口病的抵抗力,降低手足口病的发病风险。Objective:To explore the risk factors of hand,foot and mouth disease in Fuyang City.Methods:Through China Information Management System For Infectious Disease Report,a multi-stage sampling method was used to select no more than 5 years old of the registered reports from January 1,2019 to December 31,2019 from 8 townships(communities)in 2 project counties,and 197 children with hand,foot and mouth disease were selected as cases.At the same time,for each case collected,a non-hand,foot and mouth disease patient who lived in the same village(community)with the case and whose age differs from the patient by no more than 6 months was selected as controls.Conditional Logistic regression analysis was used to analyze the risk factors of incidence of hand,foot and mouth disease.Results:Univariate conditional Logistic regression analysis showed that the educational level of the guardian,the occupation of the guardian,the children's usual health status,the guardian's hand-washing before feeding the child and the vaccination status may be related to the incidence of hand,foot and mouth disease.Multivariate conditional Logistic regression analysis showed that the educational level of the guardian,the occupation of the guardian,the children's usual health status and the vaccination status were the risk factors for the incidence of hand,foot and mouth disease.Conclusion:we should strengthen the publicity and education of hand,foot and mouth disease prevention and control knowledge through various means,and improve the ability of children's guardians of different occupations to prevent and control hand,foot and mouth disease.At the same time,we should focus on children's physical activities and increase the vaccination rate of children,enhance children's resistance to hand,foot and mouth disease,and reduce the risk of hand,foot and mouth disease.

关 键 词：手足口病 危险因素 病例对照 儿童 

分 类 号：R725.1[医药卫生—儿科]