磁性发光材料的开发及其在生物医学领域中的应用  

Development of magnetic luminescent materials and their application in biomedical field

作　　者：贾园[1,2] 韩钰秋 杨菊香 刘振[1] Yuan Jia;Yuqiu Han;Juxiang Yang;Zhen Liu(School of Chemical Engineering,Xi’an University,Xi’an 710065,China;Xi’an Key Laboratory of Food Safety Testing and Risk Assessment,Xi’an 710065,China)

机构地区：[1]西安文理学院化学工程学院,西安710065 [2]西安市食品安全检测与风险评估重点实验室,西安710065

出　　处：《中国科学：化学》2022年第7期1020-1026,共7页SCIENTIA SINICA Chimica

基　　金：陕西省自然科学基础研究计划(编号:2021JQ-798);陕西省教育厅科研计划(编号:21JK0870);西安市科协青年人才托举项目(编号:095920211335);西安文理学院教学研究与改革专项项目(编号:JY2022KGE02)资助.

摘　　要：磁性发光材料同时具有磁性和发光性的特点,能够在磁场作用下发生迁移运动并进行标记,因此在生物分离、免疫检测、靶向药物、固定化酶、磁共振成像等生物医学领域具有较大的应用潜力.本文对目前磁性发光材料常见的制备方法进行了综述,详细介绍了生长组装及配合物法、掺杂法、核壳结构设计法及纳米粒子表面改性法等常用方法,并总结了其在医学检测、生物成像以及医学治疗等生物医学领域中的应用,同时展望了磁性发光材料未来的开发及应用方向.Magnetic luminescent materials have the characteristics of both magnetism and luminescence,and can migrate and label under the action of magnetic field.Therefore,they have great application potential in biological separation,immunodetection,targeted drugs,immobilized enzymes,magnetic resonance imaging,etc.In this review,common preparation methods of magnetic luminescent nanomaterials are reviewed,including assembly growth or complex method,doping method,core-shell structure design method,and surface modification method.The applications of magnetic luminescent materials in biomedical fields such as medical detection,bioimaging,and biomedical therapy are summarized,and their future development and application directions are prospected.

关 键 词：磁性材料 发光材料 医学检测 生物成像 

分 类 号：TB34[一般工业技术—材料科学与工程] R313[医药卫生—基础医学]