预后营养指数的动态评价在老年食管癌患者放射治疗期间的应用价值  

Application value of dynamic evaluation of prognostic nutritional index in elderly patients with esophageal cancer during radiotherapy

作　　者：祝丽君 吴晓燕[1] 严笑笑 ZHU Lijun;WU Xiaoyan;YAN Xiaoxiao(Department of Oncology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei,430023,China)

机构地区：[1]华中科技大学同济医学院附属协和医院肿瘤科,湖北武汉430023

出　　处：《中西医结合护理（中英文）》2022年第1期5-8,共4页Journal of Clinical Nursing in Practice

摘　　要：目的考察预后营养指数(PNI)的动态评价在老年食管癌患者放射治疗(简称“放疗”)期间的应用价值。方法选取2020年6月至2021年6月于华中科技大学同济医学院附属协和医院行放疗的100例老年食管癌患者的临床资料开展回顾性研究,按照护理方法分为对照组(40例)和观察组(60例)。对照组患者给予综合护理,观察组患者在综合护理的基础上联合PNI的动态评价。比较2组患者在干预前后的营养状况相关指标、免疫功能、生活质量及放疗期间的不良反应。结果干预3个月后,2组的营养状况相关指标均明显低于干预前(P均<0.05),但观察组均高于对照组(P均<0.05)。干预3个月后,2组的免疫功能水平均明显低于干预前(P均<0.05),但观察组均明显高于对照组(P均<0.05)。干预3个月后,2组的生活质量评分均明显高于干预前(P均<0.05),且观察组各项评分均明显高于对照组(P均<0.05)。观察组在放疗期间的不良反应总发生率明显低于对照组(P<0.05)。结论PNI的动态评价对于提高老年食管癌患者的营养状况、免疫水平和生活质量,减少放疗期间不良反应,均至关重要。Objective To investigate the application value of dynamic evaluation of prognostic nutritional index(PNI)in elderly patients with esophageal cancer during radiotherapy.Methods A retrospective study was conducted on the clinical data of 100 elderly patients with esophageal cancer who received radiotherapy at Union Hospital,Tongji Medical College,Huazhong University of Science and Technology from June 2020 to June 2021.They were assigned into a control group(40 cases)and an observation group(60 cases)according to the nursing methods.The patients in the control group were given comprehensive nursing,and the patients in the observation group adopted dynamic evaluation of PNI on the basis of comprehensive nursing.The nutritional status indicators,immune function,and quality of life before and after intervention,as well as the side effects during radiotherapy,were compared between the two groups.Results After 3 months of intervention,the nutritional status indicators of the two groups were significantly lower than those before intervention(all P<0.05),but the indicators of the observation group were higher than those of the control group(all P<0.05).After 3 months of intervention,the immune function level of the two groups was significantly lower than that before intervention(all P<0.05),but the level of the observation group was significantly higher than that of the control group(all P<0.05).After 3 months of intervention,the scores of quality of life in the two groups were significantly higher than those before intervention(all P<0.05),and the scores of various items of the observation group were significantly higher than those of the control group(all P<0.05).The total incidence of side effects during radiotherapy in the observation group was significantly lower than that in the control group(P<0.05).Conclusion The dynamic evaluation of PNI plays a crucial role in improving the nutritional status,immune function,and quality of life of elderly patients with esophageal cancer,and reducing the side effects during radio

关 键 词：食管癌 放射治疗 预后营养指数 生活质量 

分 类 号：R473.73[医药卫生—护理学]