基于三维正交条形碲锌镉探测器的DOI-PET显像研究  

DOI-PET Imaging Investigation Based on 3-D Cross-Strip Cadmium Zinc Telluride Detector

作　　者：李英帼 崔振存 郭典 刘美楼 文婧 张庆华 裴昌旭 黄川 尹永智[1] 李公平[1] LI Yingguo;CUI Zhencun;GUO Dian;LIU Meilou;WEN Jing;ZHANG Qinghua;PEI Changxu;HUANG Chuan;YIN Yongzhi;LI Gongping(School of Nuclear Science and Technology,Lanzhou University,Lanzhou 730000,China;Department of Nuclear Medicine,Second Hospital of Lanzhou University,Lanzhou 730000,China)

机构地区：[1]兰州大学核科学与技术学院,兰州730000 [2]兰州大学第二医院核医学科,兰州730000

出　　处：《同位素》2022年第4期242-247,I0001,共7页Journal of Isotopes

基　　金：国家自然科学基金面上项目(11875156);兰州大学中央高校基本科研业务费专项资金资助(lzujbky-2021-ct02)。

摘　　要：为对511 keV伽马光子进行三维定位,提高PET显像性能,研制一种尺寸为16.4 mm×16.4 mm×5 mm正交条形碲锌镉(CZT)探测器,并测试其PET显像性能。在32个电极读出后均采用电荷灵敏前置放大器和滤波放大模块,输入高速模数转换器对数据进行采样,得到探测器中信号的全脉冲形状,并利用模拟数字转换器(ADC)内置可编程门列阵(FPGA)对信号进行在线处理,对信号完成寻峰、滤波等数字化处理。结果表明,该碲锌镉探测器对511 keV伽玛光子的能量分辨率为6.35%,通过对碲锌镉探测器的电极结构分析得出了一套伽马光子相互作用的三维位置坐标计算公式,可以达到亚毫米位置分辨率,实现了碲锌镉探测器三维显像功能。To study the PET imaging performance of cross-strip cadmium zinc telluride detector with a size of 16.4 mm×16.4 mm×5 mm,which can determine the 3-D position information of 511 keV gamma photons.The 32 electrodes of the detector are all read out using charge sensitive preamplifiers and filter amplification modules,and then input high-speed analog-to-digital converters to sample the data,and obtain the full pulse shape of the signal in the detector,and use the ADC built-in FPGA to perform the online signal processing,digital processing such as peak finding and filtering.The energy resolution of the CZT detector for 511 keV gamma photons is 6.35%.According to the electrode structure of the CZT detector,3-D position coordinate calculation formulas for the interaction of gamma photons can be obtained.The CZT detector realizes a 3-D imaging function with a sub-millimeter resolution.

关 键 词：正交条形CZT探测器 三维定位 能量分辨率 PET显像 

分 类 号：TL814[核科学技术—核技术及应用]