从升降相因诊治干燥综合征  

Diagnosis and treatment of Sjogren syndrome based on ascending and descending theory

作　　者：沈正东 徐江喜 张赛[1] 张玉婷[1] 刘小平[2] 朱跃兰[2] SHEN Zheng-dong;XU Jiang-xi;ZHANG Sai;ZHANG Yu-ting;LIU Xiao-ping;ZHU Yue-lan(Beijing University of Chinese Medicine,Beijing 100029,China;Department of Rheumatology,Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China)

机构地区：[1]北京中医药大学,北京100029 [2]北京中医药大学东方医院风湿科,北京100078

出　　处：《中华中医药杂志》2022年第7期3901-3904,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81874438)。

摘　　要：干燥综合征是以外分泌腺受损为主,并累及皮肤、肌肉、骨骼、肺、肾等多个脏器的系统性自身免疫性疾病,归属于中医燥痹。阴虚为本,燥毒为标是近代学者的主流观点,然而临床应用滋阴清燥之法往往不能取得满意的效果。作者认为干燥综合征患者阴虚燥盛,久则气血痹阻、燥毒随经流窜四肢百骸,形成燥、毒、瘀胶着互结之势,同时存在气的升降相因失调。故文章将从升降相因理论出发探讨干燥综合征患者的病机,以期为干燥综合征的诊治提供思路和借鉴。Sjogren syndrome is a systemic autoimmune disease with damage of exocrine glands and involving multiple organs such as skin, musculoskeletal, lung and kidney. It can be attributed to the category of ‘dryness’ in traditional Chinese medicine. Deficiency of yin and dryness toxin are the mainstream views of modern scholars. However, the clinical application of nourishing yin and clearing dryness often can not achieve expected results. The author considers that patients with Sjogren syndrome are deficiency of yin and abundance of dryness. Qi and blood are blocked while dryness and toxin flow with the meridians, forming the tendency of dryness, poison and blood stasis, and there is an imbalance in ascending and descending of qi in the long course of disease. Therefore, this paper will discuss the pathogenesis of Sjogren syndrome from the theory of ascending and descendin, in order to provide ideas and reference for the diagnosis and treatment of Sjogren syndrome.

关 键 词：干燥综合征 燥痹 升降相因 燥毒瘀 

分 类 号：R259[医药卫生—中西医结合]