子宫肌瘤孕妇子宫肌瘤大小、数目与临床参数的相关性  

Correlation between the size,number of uterine fibroids and clinical parameters in pregnant women with uterine fibroids

作　　者：施兴华 黄海燕 居仁婷 张帅赛 SHI Xinghua;HUANG Haiyan;JU Renting;ZHANG Shuaisai(Department of Obstetrics and Gynecology,Qidong Maternal and Child Health Hospital,Jiangsu Province,Qidong 226200,China;Department of Obstetrics and Gynecology,Nantong Maternal and Child Health Hospital,Jiangsu Province,Nantong 226000,China)

机构地区：[1]江苏省启东市妇幼保健院妇产科,江苏启东226200 [2]江苏省南通市妇幼保健院妇产科,江苏南通226000

出　　处：《妇儿健康导刊》2022年第8期34-36,40,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

基　　金：江苏省南通市妇幼健康专科联盟科研项目(TFM202001)。

摘　　要：目的探讨子宫肌瘤孕妇子宫肌瘤大小、数目与临床参数间的相关性。方法选择2014年2月至2019年2月于启东市妇幼保健院与南通市妇幼保健院分娩、同期行子宫肌瘤手术的219例孕妇为观察组。根据子宫肌瘤的数目分为多发肌瘤组和单发肌瘤组,根据肌瘤大小分为大肌瘤组和小肌瘤组,选择均衡年龄的219例产妇为对照组,比较各组围产结局和Apgar评分。采用Pearson相关性分析方法对孕妇子宫肌瘤大小与临床参数的相关性进行分析。结果多发肌瘤组早产、臀先露和剖宫产率高于对照组和单发肌瘤组(P<0.05);单发肌瘤组未足月胎膜早破(pPROM)检出率高于对照组(P<0.05)。大肌瘤组早产率高于对照组(P<0.05);大肌瘤组和小肌瘤组pPROM检出率高于对照组(P<0.05)。相关性分析结果提示,子宫肌瘤孕妇子宫肌瘤大小与孕龄呈正相关(P<0.05),与出生体重呈负相关(P<0.05),但是剖宫产、前置胎盘、胎盘早剥、胎儿宫内生长受限(IUGR)和出生时Apgar评分与之无关(P>0.05)。结论子宫肌瘤孕妇子宫肌瘤大小及数目会对围产结局产生影响且与临床参数存在相关性,应积极采取干预措施,改善妊娠结局。Objective To explore the correlation between the size,number of uterine fibroids and clinical parameters in pregnant women with uterine fibroids.Methods A total of 219 puerpera who gave birth in Qidong Maternal and Child Health Hospital and Nantong Maternal and Child Health Hospital from February 2014 to February 2019 and underwent uterine fibroid surgery during the same period were selected as the observation group.According to the number of uterine fibroids,they were divided into multiple fibroids group and single fibroids group,and they were divided into large fibroids group and small fibroids group according to the size of fibroids,219 puerpera with balanced age were selected as control group,and perinatal outcomes and Apgar scores of each group were compared.Pearson correlation was used for analysis of the correlation between the s ize of uterine fibroids and clinical param eters.Results The rates of premature birth,breech presentation and cesarean section in the multiple fibroids group were higher than those in the control group and the single fibroids group(P<0.05).The detection rate of preterm premature rupture of membranes(pPROM)in the single fibroids group was higher than that in the control group(P<0.05).The preterm birth rate in the large fibroids group was higher than that in the control group(P<0.05).The detection rate of pPROM in the large fibroids group and the small fibroids group was higher than that in the control group(P<0.05).The results of correlation analysis showed that uterine fibroids size was positively correlated with gestational age(P<0.05),negatively correlated with birth weight(P<0.05),however,cesarean section,placenta previa,placental abruption,intrauterine growth restriction(IUGR)and Apgar score at birth were not associated with it(P>0.05).Conclusion The size and number of uterine fibroids in pregnant women with uterine fibroids have an impact on perinatal outcomes and are correlated with clinical parameters.Active intervention measur es should be taken to improve pregna ncy outco

关 键 词：子宫肌瘤 子宫肌瘤大小 围产结局 临床参数 相关性 干预措施 

分 类 号：R711[医药卫生—妇产科学]