青少年脊柱侧凸手术后急性肾损伤的发生率及相关因素  

Incidence and related factors of acute kidney injury after scoliosis surgery in adolescent patients

作　　者：胡袒 向明祥 HU Tan;XIANG Ming-xiang(People's Hospital of Yunyang County,Chongqing,404500,China)

机构地区：[1]重庆市云阳县人民医院,重庆404500

出　　处：《颈腰痛杂志》2022年第4期505-507,共3页The Journal of Cervicodynia and Lumbodynia

基　　金：宁夏回族自治区自然科学基金(编号:NZ16212)。

摘　　要：目的探讨青少年脊柱侧凸手术后急性肾损伤(acute kidney injury,AKI)的发生率及相关因素。方法选择2001年1月~2019年12月在本院接受手术治疗的713例脊柱侧凸青少年患者,以围手术期是否发生AKI将其分为AKI组和非AKI组,观察两组患者临床资料差异。结果713例患者围手术期AKI发生率为3.23%。AKI和非AKI患者的性别、贫血、血小板减少、凝血异常、横纹肌溶解、使用右美托咪啶等资料存在统计学差异(P<0.05)。二分类多因素Logisitc分析显示,男性、横纹肌溶解是AKI的风险因素(P<0.05),术中使用右美托咪定是AKI的保护性因素(P<0.05)。结论AKI是特发性脊柱侧凸青少年患者术后重要并发症,性别、横纹肌溶解和书中使用右美托咪啶均可影响AKI发生。Objective To investigate the incidence and related factors of acute kidney injury(AKI)after scoliosis surgery in adolescent patients.Methods From January 2001 to December 2019,713 patients with scoliosis who received surgical treatment in our hospital were selected as the research objects.The patients were divided into AKI group and non-AKI group according to whether AKI occurred during perioperative period.The differences of clinical data between the two groups were observed.Results The incidence rate of AKI in 713 patients was 3.23%.There were significant differences in gender,anemia,thrombocytopenia,coagulation abnormalities,rhabdomyolysis,dexmedetomidine between AKI and non-AKI patients(P<0.05).Binary logistic analysis showed that male and rhabdomyolysis were risk factors of AKI(P<0.05),and dexmedetomidine was a protective factor of AKI(P<0.05).Conclusion AKI is an important postoperative complication in adolescent patients with idiopathic scoliosis.Gender,rhabdomyolysis and dexmedetomidine can affect AKI.

关 键 词：脊柱侧凸 急性肾损伤 发生率 风险因素 

分 类 号：R619[医药卫生—外科学]