HIV感染母亲分娩未感染婴幼儿的生长发育调查及干预对策  

Investigation on growth and development of uninfected infants delivered by HIV-infected mothers and intervention strategies

作　　者：胡丹[1] 朱炜春 王周菊 HU Dan;ZHU Weichun;WANG Zhouju(Department of Pediatrics of Guangzhou Eighth Hospital of Guangzhou Medical University,Guangzhou 510000 Guangdong,China)

机构地区：[1]广州医科大学附属市八医院儿科,广东广州510000

出　　处：《中国民康医学》2022年第14期15-17,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:分析人类免疫缺陷病毒(HIV)感染母亲分娩未感染婴幼儿的生长发育情况和干预对策。方法:回顾性分析2017年1月至2019年6月该院收治的86例HIV感染母亲分娩的婴幼儿的临床资料,设为观察组;同期该院收治的健康产妇分娩的86名足月儿的临床资料,设为对照组。比较两组婴幼儿体格生长发育指标(头围、体质量、身长)水平、智力发育状况和营养性疾病发病率。结果:出生时及出生3、6、12、18个月时,观察组体质量均低于对照组,身长均短于对照组,差异有统计学意义(P<0.05);出生3、6、12、18个月时,观察组头围均小于对照组,差异有统计学意义(P<0.05);出生12、18个月时,观察组言语、个人-社会智力评分均低于对照组,差异有统计学意义(P<0.05);出生12、18个月时,两组粗动作、细动作-适应性智力评分比较,差异无统计学意义(P>0.05);出生后随访18个月,观察组营养性疾病发病率为17.44%,明显高于对照组的4.65%,差异有统计学意义(P<0.05)。结论:HIV感染母亲分娩未感染婴幼儿出生后的体格生长发育和智力发育状况均较正常分娩的健康足月儿迟缓,且发生营养性疾病的风险高。Objective:To analyze growth and development of uninfected infants delivered by human Immunodeficiency virus(HIV)-infected mothers and intervention strategies.Methods:The clinical data of 86 infants delivered by HIV-infected mothers admitted to our hospital from January 2017 to June 2019 were retrospectively analyzed,and they were set as observation group.The clinical data of 86 full-term infants delivered by healthy puerperae admitted to the hospital during the same period were retrospectively analyzed,and they were set as control group.The levels of physical growth and development indicators(head circumference,body weight,body length),the mental development status,and the incidence of nutritional diseases were compared between the two groups.Results:At birth,3 months,6 months,12 months and 18 months,the body weight of the observation group was lower than that of the control group,the body length of the observation group was shorter than that of the control group,and the differences were statistically significant(P<0.05).At 3 months,6 months,12 months and 18 months,the head circumference of the observation group was smaller than that of the control group,and the difference was statistically significant(P<0.05).At 12 months and 18 months after birth,the scores of speech and personal-social intelligence in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).At 12 months and 18 months after birth,there were no significant differences in gross motor and fine motor-adaptive intelligence scores between the two groups(P>0.05).During the 18-month follow-up after birth,the incidence of nutritional diseases in the observation group was 17.44%,which was significantly higher than the control group of 4.65%,and the difference was statistically significant(P<0.05).Conclusions:The uninfected infants delivered by the HIV-infected mothers have slower physical growth and intellectual development than the healthy full-term infants delivered by the healthy puerp

关 键 词：HIV感染 孕妇 婴幼儿 体质量 身高 头围 智力 

分 类 号：R72[医药卫生—儿科]