聚醚醚酮与钛网材料在颅骨缺损后修补术中的应用  

Application of PEEK and titanium mesh in cranioplasty

作　　者：祝展鹏 杨佳 谢宝树 邓景阳 曾志明 祝刚 ZHU Zhanpeng;YANG Jia;XIE Baoshu;DENG Jingyang;ZENG Zhiming;ZHU Gang(Graduate School of Guangdong Medical University,Zhanjiang 524023,China;Dongguan Songshanhu Central Hospital,Dongguan 523200,China;The First Affiliated Hospital of Sun-Yatsen University,Guangzhou 510000,China;Huizhou Central People’s Hospital,Huizhou 516001,China)

机构地区：[1]广东医科大学研究生院,广东湛江524023 [2]东莞松山湖中心医院,广东东莞523200 [3]中山大学附属第一医院,广东广州510000 [4]惠州市中心人民医院,广东惠州516001

出　　处：《中国实用神经疾病杂志》2022年第6期674-678,共5页Chinese Journal of Practical Nervous Diseases

基　　金：广东省基础与应用基础研究基金(编号:2019A1515110460)。

摘　　要：目的探讨聚醚醚酮(PEEK)及钛网在颅骨损伤后修补术中的应用效果。方法回顾性分析接受颅骨修补术的200例患者临床资料,其中121例采用PEEK材料(PEEK组),79例采用钛网(钛网组)。分析并比较2组患者的手术时间、术中出血量、术中并发症(硬膜破裂)、术后并发症(感染、材料外露、排异)。结果PEEK组和钛网组手术出血量无明显差异[(94.13±80.82)mL vs(104.50±94.73)mL,P>0.05];PEEK组平均手术时长大于钛网组[(171.24±78.48)min vs(138.54±58.63)min],差异有统计学意义(P<0.05);修补后因并发症材料取出8例,PEEK组3例(3/121),钛网组5(5/79);切口感染5例(PEEK组3例,钛网组2例),材料外露2例,排异反应1例,2组并发症发生率比较无显著性差异(P>0.05)。结论PEEK和钛网两种修补材料各具有优势,个体化治疗方案能达到颅骨缺损患者的最优治疗效果。Objective To investigate the effect of polyether ether ketone(PEEK)and titanium mesh in the repair of skull injury.Methods Clinical data of 200 neurosurgical patients who underwent skull repair were analyzed retrospectively,121 cases were treated with PEEK material(PEEK group)and 79 cases were treated with titanium mesh(titanium mesh group);The operation time,intraoperative bleeding,intraoperative complica⁃tions(dural rupture)and postoperative complications(infection,material exposure,rejection)were analyzed and compared between the two groups.Results There was no significant difference in the amount of bleeding be⁃tween peek group and titanium mesh group(94.13±80.82)mL vs(104.50±94.73)mL,P>0.05).After repair,ma⁃terials were removed in 8 cases due to complications,including 3 cases in peek group(3/121),5 cases in titanium mesh group(5/79),5 cases of incision infection(3 cases in PEEK group and 2 cases in titanium mesh group),2 cases of material exposure and 1 case of rejection reaction.There was no significant difference on complications(P>0.05).Conclusion PEEK and titanium mesh have their own advantages.Individualized treatment plan can achieve optimal treatment effect in patients with skull defect.

关 键 词：颅骨缺损 颅骨修补 骨修补材料 聚醚醚酮 钛网 并发症 

分 类 号：R683.5[医药卫生—骨科学]