Leaf morphogenesis:The multifaceted roles of mechanics  

作　　者：Kexin Guo Changjin Huang Yansong Miao Daniel J.Cosgrove K.Jimmy Hsia 

机构地区：[1]School of Mechanical and Aerospace Engineering,Nanyang Technological University,Singapore 639798,Singapore [2]School of Biological Sciences,Nanyang Technological University,Singapore 637551,Singapore [3]Department of Biology,The Pennsylvania State University,University Park,PA 16802,USA [4]School of Chemical and Biomedical Engineering,Nanyang Technological University,Singapore 637459,Singapore

出　　处：《Molecular Plant》2022年第7期1098-1119,共22页分子植物（英文版）

基　　金：support from Nanyang Technological University(grant no.M4082428);K.J.H.and C.H.acknowledge support from Nanyang Technological University under its Accelerating Creativity and Excellence(ACE)grant(grant no.NTU-ACE2020-07);supported by the Center for Engineering Mechano Biology,an National Science Foundation(NSF)Science and Technology Center,under grant agreement No.CMMI:15-48571;supported by the U.S.Department of Energy(grant no.DE-FG2-84ER13179);support from the Ministry of Education-Singapore,under its Academic Research Fund Tier 1(RT11/20 and RG32/20).

摘　　要：Plants produce a rich diversity of biological forms,and the diversity of leaves is especially notable.Mechanisms of leaf morphogenesis have been studied in the past two decades,with a growing focus on the interactive roles of mechanics in recent years.Growth of plant organs involves feedback by mechanical stress:growth induces stress,and stress affects growth and morphogenesis.Although much attention has been given to potential stress-sensing mechanisms and cellular responses,the mechanical principles guiding morphogenesis have not been well understood.Here we synthesize the overarching roles of mechanics and mechanical stress in multilevel and multiple stages of leaf morphogenesis,encompassing leaf primordium initiation,phyllotaxis and venation patterning,and the establishment of complex mature leaf shapes.Moreover,the roles of mechanics at multiscale levels,from subcellular cytoskeletal molecules to single cells to tissues at the organ scale,are articulated.By highlighting the role of mechanical buckling in the formation of three-dimensional leaf shapes,this review integrates the perspectives of mechanics and biology to provide broader insights into the mechanobiology of leaf morphogenesis.

关 键 词：leaf morphogenesis cell-wall mechanics phyllotaxis and venation patterning differential and anisotropic growth mechanical buckling 

分 类 号：Q943.2[生物学—植物学]