灸法治疗中晚期癌症患者癌因性疲乏的系统评价和Meta分析  

Systematic Evaluation and Meta-Analysis of Moxibustion in the Treatment of Cancer-Related Fatigue in Patients with Intermediate and Terminal Cancer

作　　者：赵玢 黄仙保 李巧林[2] 郑鹏炜 蓝荣林 ZHAO Bin;HUANG Xian-bao;LI Qiao-lin;ZHENG Peng-wei;LAN Rong-lin(The 2020 Master Degree Candidate of Jiangxi University of Chinese Medicine,Nanchang330004;The Affiliated Hospital of Jiangxi University of TCM,Nanchang 330006;The 2021 Master Degree Candidate of Jiangxi University of Chinese Medicine,Nanchang330004)

机构地区：[1]江西中医药大学,南昌330004 [2]江西中医药大学附属医院,南昌330006

出　　处：《实用中西医结合临床》2022年第10期92-97,共6页Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine

基　　金：江西省教育厅科学技术研究项目(编号:GJJ190655);江西省卫生健康委技术计划项目(编号:SKJP220202783);江西中医药大学校级研究生创新专项基金项目(编号:JZYC21S67)。

摘　　要：目的:运用Meta分析方法对目前灸法治疗中晚期癌症患者癌因性疲乏的疗效与安全性做出客观评价。方法:对中国生物医学文献数据库(CBM disc)、中国知网(CNKI)、维普(VIP)、万方(WF)、PubMed、EMBASE、Cochrance Library、Web of Science八大数据库系统展开全面检索,并辅以江西中医药大学图书馆过刊资料库的人工查阅,采集灸法治疗中晚期癌症患者癌因性疲乏的随机对照临床试验文献,将检索时间定为各个数据库建库至2022年2月19日,并通过Cochrane偏倚风险评价工具对已纳入文献展开质量评估,最后再运用RevMan5.3应用软件展开统计与分析。结果:最终纳入16篇文献,共计1355例病例。Meta分析结果表明,灸法在治疗中晚期癌症患者癌因性疲乏的总有效率、Piper评分量表评分、卡式(Karnofsky)功能状态评分(KPS)、简易疲乏量表评分、EORTC-QLQ-C30评分均比对照组更优。结论:灸法治疗中晚期癌症患者癌因性疲乏的疗效肯定,且安全性高,但仍需更多质量较高、样本数量更大、多中心的随机对照试验加以印证。Objective:To evaluate the efficacy and safety of moxibustion in the treatment of cancer-related fatigue in patients with intermediate and terminal cancer by using meta analysis.Methods:A comprehensive search was carried out on the eight database systems of China biomedical literature database(CBM disc),China National Knowledge Network(CNKI),VIP,WF,PubMed,EMBASE,Cochrane Library,and Web of Science,supplemented by manual access to the back issue database of the library of Jiangxi University of traditional Chinese Medicine,collected randomized controlled clinical trial literature on moxibustion in the treatment of cancer-related fatigue in patients with intermediate and terminal cancer,the retrieval time was set for the establishment of each database to February 19,2022,and the quality of the included literature was evaluated through the Cochrane bias risk assessment tool.Finally,Revman5.3 application software was used for statistics and analysis.Results:Finally,16 literatures were included,with a total of 1355 cases.The results of meta-analysis showed that the total effective rate,Piper score scale score,Karnofsky functional state score(KPS),simple fatigue scale score and EORTC-QLQ-C30 score of moxibustion in the treatment of cancer-related fatigue in patients with intermediate and terminal cancer were better than those in the control group.Conclusion:Moxibustion is effective and safe in the treatment of cancer-related fatigue in patients with intermediate and terminal cancer,but it still needs to be confirmed by more randomized controlled trials with higher quality,larger sample size and multiple centers.

关 键 词：癌因性疲乏 中晚期癌症 灸法 META分析 

分 类 号：R245.8[医药卫生—针灸推拿学]