Histoacryl■组织胶超选择性栓塞肾动脉分支治疗医源性肾动脉出血  

Superselective embolization of renal artery branch with Histoacryl■ tissue glue for treating iatrogenic renal artery hemorrhage

作　　者：许凯豪 宋梦瑶 焦德超[1] 韩新巍[1] 孙占国 方毅[1] 闫焱[2] XU Kaihao;SONG Mengyao;JIAO Dechao;HAN Xinwei;SUN Zhanguo;FANG Yi;YAN Yan(Department of International Radiology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Oncology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院放射介入科,河南郑州450052 [2]郑州大学第一附属医院肿瘤科,河南郑州450052

出　　处：《中国介入影像与治疗学》2022年第8期449-453,共5页Chinese Journal of Interventional Imaging and Therapy

基　　金：河南省高等学校重点科研项目(20A320065)。

摘　　要：目的观察以Histoacryl■组织胶作为栓塞剂超选择性栓塞肾动脉分支治疗医源性肾动脉出血的效果。方法回顾性分析52例医源性肾动脉出血患者,其中30例为经皮肾镜术后、15例为经皮肾穿刺活检术后、7例为部分肾切除术后;均接受数字减影血管造影(DSA)引导下超选择性栓塞患肾责任分支动脉,栓塞剂为Histoacryl■组织胶。评价技术成功率、临床成功率、并发症及操作时间,比较栓塞前、后血红蛋白(Hb)、肌酐(Cr)和尿素氮(BUN)。结果对52例均顺利完成治疗,平均操作时间(38.23±11.51)min,技术成功率、临床成功率均为100%。术前2 h与术后12 h内Hb、Cr及BUN差异均无统计学意义(P均>0.05)。术后4例(4/52,7.69%)出现轻微并发症(发热伴局部腰痛),经对症及支持治疗后恢复;无肾脓肿、败血症、肾破裂等严重并发症发生。结论以Histoacryl■组织胶作为栓塞剂超选择性栓塞肾动脉分支治疗医源性肾动脉出血安全、有效。Objective To observe the effects of superselective embolization of renal artery branch with Histoacryl■ tissue glue for treating iatrogenic renal artery hemorrhage. Methods Data of 52 patients with iatrogenic renal artery hemorrhage, including 30 cases after percutaneous nephroscopy, 15 after percutaneous renal biopsy and 7 cases after partial nephrectomy who underwent superselective embolization of renal artery branch with Histoacryl■ tissue glue under the guidance of digital subtraction angiography(DSA) were retrospectively analyzed. The technical success rate, clinical success rate, complications and operation time were evaluated, and the preoperative and postoperative hemoglobin(Hb), creatinine(Cr) and urea nitrogen(BUN) were compared. Results Superselective embolization of renal artery branch was successfully performed in all 52 cases, with the average operation time of(38.23±11.51)min. The technical success rate and clinical success rate were both 100%. No significant difference of Hb, Cr nor BUN between 2 h before and 12 h after embolization(all P>0.05). Minor complications(fever with local lumbago) occurred in 4 patients(4/52, 7.69%) after embolization, and then recovered after symptomatic support treatments. No serious complication, such as renal abscess, sepsis nor renal rupture occurred. Conclusion Superselective embolization of renal artery branch with Histoacryl■ tissue glue was safe and effective for treating iatrogenic renal artery hemorrhage.

关 键 词：肾动脉 医源性出血 栓塞 治疗性 组织胶 

分 类 号：R692.9[医药卫生—泌尿科学] R815[医药卫生—外科学]