三伏天灸配合隔姜灸与单一疗法防治支气管哮喘比较研究  

Comparative Study on Moxibustion in Dog Days Combined with Moxibustion on Ginger and Monotherapy in the Prevention and Treatment of Bronchial Asthma

作　　者：高乐女 陈大为[2] 段海玲 王勇 GAO Lenv;CHEN Dawei;DUAN Hailing;WANG Yong

机构地区：[1]陆军军医大学第一附属医院中医与风湿免疫科,重庆400038 [2]重庆医科大学附属第一医院康复科,重庆400016 [3]陆军军医大学第一附属医院呼吸与危急重症科,重庆400038

出　　处：《新中医》2022年第14期164-169,共6页New Chinese Medicine

基　　金：重庆市科卫联合中医药科技项目(ZY201802114)。

摘　　要：目的:观察并比较三伏天穴位中药贴敷联合隔姜灸与单一疗法(三伏天灸或隔姜灸)治疗支气管哮喘的临床疗效。方法:选取处于慢性持续期或临床缓解期的支气管哮喘患者44例,随机分为3组。在2020年三伏天期间,综合组14例予三伏天灸联合隔姜灸治疗;天灸组16例予天灸治疗,隔姜灸组14例予隔姜灸治疗,治疗3次为1个疗程。在治疗前,治疗后第16,32和48周时,通过哮喘控制评分(Asthma control test score,ACT)评估疾病的控制情况。并于治疗前后检测患者外周血嗜酸性粒细胞计数。结果:3例退出试验。纳入统计者综合组13例,天灸组15例,隔姜灸组13例。治疗后随访1年,天灸组支气管哮喘年度发作次数治疗前后比较,差异有统计学意义(P<0.05)。但3组间支气管哮喘年度发作次数比较,差异无统计学意义(P>0.05)。与治疗前比较,天灸组ACT评分从第32周开始改善,并持续至第48周,差异均有统计学意义(P<0.05);综合组ACT评分改善于48周后,差异有统计学意义(P<0.05);隔姜灸组ACT评分治疗前后比较,差异无统计学意义(P>0.05)。治疗后,综合组和隔姜灸组患者的外周血嗜酸性粒细胞计数分别与治疗前比较,差异均无统计学意义(P>0.05);天灸组外周血嗜酸性粒细胞计数较治疗前降低,差异有统计学意义(P<0.05)。3组治疗后外周血嗜酸性粒细胞计数比较,差异无统计学意义(P>0.05)。治疗后随访1年,3组年度医疗费用前后比较,差异无统计学意义(P>0.05)。3组间年度医疗费用比较,差异无统计学意义(P>0.05)。结论:三伏天灸有助于减少哮喘发作和外周血嗜酸性粒细胞计数,是治疗支气管哮喘更有效、更便捷的方法。Objective:To observe and compare the clinical effect of the therapy of moxibustion in dog days combined with moxibustion on ginger and monotherapy(moxibustion in dog days or moxibustion on ginger)on the prevention and treatment of bronchial asthma.Methods:A total of 44 patients with bronchial asthma in chronic duration or clinical remission were randomly assigned into three groups.During the dog days of 2020,fourteen patients in the integrated group were treated with moxibustion in dog days combined with moxibustion on ginger.Sixteen patients in the moxibustion in dog days group were treated with moxibustion in dog days,and fourteen cases in the moxibustion on ginger group were treated with moxibustion on ginger.All groups were treated for one course,three times being a course.Before treatment,and 16,32,and 48 weeks after treatment,the disease control was assessed by Asthma Control Test(ACT).The eosinophil count in peripheral blood was measured before and after treatment.Results:Three cases dropped out from the experiment.Included in the statistics were 13 cases in the integrated group,15 cases in the moxibustion in dog days group and 13 cases in the moxibustion on ginger group.After one year of follow-up,there was significant significance in the annual attack of bronchial asthma before and after treatment in the moxibustion in dog days group,the difference being significant(P<0.05),but there was no significant difference in the annual attack of bronchial asthma among the three groups(P>0.05).When compared with that before treatment,the ACT score in the moxibustion in dog days group was improved from Week 32 and lasted to Week 48,differences being significant(P<0.05);the ACT score in the integrated group was improved after Week 48,the difference being significant(P<0.05);there was no significant difference in the ACT score before and after treatment in the moxibustion on ginger group(P>0.05).After treatment,there was no significant difference in the eosinophil count in the integrated group and the moxibustion on

关 键 词：支气管哮喘 三伏天灸 隔姜灸 穴位敷贴 

分 类 号：R562.25[医药卫生—呼吸系统]