“Living”fluorophores:thermo-driven reversible ACQ-AIE transformation and ultra-sensitive in-situ monitor for dynamic Diels-Alder reactions  

作　　者：Danning Hu Hongye Huang Ruoxin Li Jinying Yuan Yen Wei 

机构地区：[1]Key Laboratory of Bioorganic Phosphorus Chemistry&Chemical Biology,Department of Chemistry,Tsinghua University,Beijing 100084,China [2]Key Laboratory of Organic Optoelectronics&Molecular Engineering of Ministry of Education,Department of Chemistry,Tsinghua University,Beijing 100084,China

出　　处：《Science China Chemistry》2022年第8期1532-1537,共6页中国科学（化学英文版）

基　　金：supported by the National Natural Science Foundation of China(21788102)。

摘　　要：Organic fluorophores play essential roles in both academic and applied fields.Most of the fluorescent molecules can be divided into aggregation-caused quenching(ACQ)and aggregation-induced emission(AIE)types based on the diverse emission properties in solution and aggregated states.Currently,a large part of studies focuses on the ACQ-to-AIE one-way transformation and the complex synthesis of chemical bonds is inevitable in all existing methods.To maximize the advantages of ACQ and AIE types fluorophores and avoid complex chemosynthesis,we propose a facile strategy first realizing the reversible ACQAIE transformation with the dynamic Diels-Alder(DA)reactions.Besides,the fluorescent platform can monitor DA reactions in microscale ultra-sensitively and quantitively.The dynamic covalent bonds can help to develop novel fluorophores creatively,and the reversible ACQ-AIE platform is expected to offer fresh insights into the dynamic covalent chemistry.

关 键 词：Diels-Alder reaction dynamic covalent chemistry aggregation-induced emission aggregation-caused quenching fluorescence sensor reaction monitor 

分 类 号：O644.1[理学—物理化学]