一款含死海水乳液的抗衰功效评价研究  

Study on the anti-aging efficacy of the Dead Sea water emulsion

作　　者：牛文霞 何先喆 韩兴艳 Wenxia Niu;Xianzhe He;Xingyan Han(Fosun Cosmetics(Shanghai)Bio-Technology Co.,Ltd.,Shanghai 200233,China)

机构地区：[1]星智豫美(上海)生物科技有限公司,上海200233

出　　处：《日用化学工业》2022年第8期851-857,共7页China Surfactant Detergent & Cosmetics

摘　　要：为研究死海水对人体皮肤的抗衰功效,以一款含死海水的乳液配方进行了皮肤抗衰老功效验证,以客观测试数据及主观评价结合法对皮肤各项指标进行8周试用评估。筛选30名27~57岁女性受试者作为研究对象,采用随机双盲对照实验,分别在使用产品2周,4周,8周后采集受试者两侧脸颊的皮肤角质层水分含量、经皮失水量、皮肤弹性、C-Cube皱纹3D图像以及受试者自我评价数据。结果显示,8周后使用含死海水乳液一侧面部皮肤状态得到显著改善(P<0.05),角质层水分含量增加17.77%,经皮失水量降低11.29%,皮肤弹性提升17.62%,法令纹深度降低18.23%,眼角纹降低16.71%,各项指标均优于对照组结果,结合受试者各阶段逐渐上升的自我评分结果说明死海水应用到乳液中具有良好的抗衰效果。Combined with objective test data and subjective evaluation method,an 8-week trial was conducted to evaluate the anti-aging efficacy of the Dead Sea water emulsion.Thirty eligible subjects(27-57 years old,female)were selected for this randomized double-blind controlled experiment.3D images of wrinkles,stratum corneum moisture content,transepidermal water loss and skin elasticity on both cheeks were collected by researchers at 2 weeks,4 weeks and 8 weeks after using the Dead Sea water emulsion.Subjects were also asked to make a self-assessment of their skin condition at each period.The comprehensive evaluation results show that,all skin indexes of the subjects are gradually improved as the trial duration grows.The 8-week data of facial skin condition are significantly improved after using the Dead Sea water emulsion(P<0.05).The stratum corneum moisture content is increased by 17.77%;the transepidermal water loss is decreased by 11.29%;the skin elasticity is increased by 17.62%;the depth of nasolabial folds is decreased by 18.23%;the wrinkles of canthus are decreased by 16.71%.The results of all indexes are better than the blank control group.In addition,the self-rating of subjects is also gradually increased in each period.In conclusion,the Dead Sea water applied in emulsion has obviously improved the anti-aging efficacy.

关 键 词：死海水 抗衰老 临床功效 

分 类 号：TQ658[化学工程—精细化工]