3.0 T MRI 3种扫描序列对腰椎小关节软骨成像的对比研究  

Comparative study on three kinds of 3.0 T MRI sequences for lumbar facet joint cartilage

作　　者：罗慕晴 李宏伟 张堃[1] 马孟甜 廖云杰[3] 颜路悠 高辉 李平[1] LUO Muqing;LI Hongwei;ZHANG Kun;MA Mengtian;LIAO Yunjie;Yan Luyou;GAO Hui;LI Ping(Department of Radiology,First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410007,China;Department of Radiology,Huaihua Hospital of Traditional Chinese Medicine,Huaihua 418099,China;Department of Radiology,the Third Xiangya Hospital of Central South University,Changsha 410003,China)

机构地区：[1]湖南中医药大学第一附属医院放射科,长沙410007 [2]怀化市中医医院影像科,怀化418099 [3]中南大学湘雅三医院放射科,长沙410003

出　　处：《磁共振成像》2022年第8期65-70,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金青年科学基金(编号:81603482);湖南中医药大学重点学科建设项目(编号:4901-020000200806)。

摘　　要：目的比较3种3.0 T MRI扫描序列对腰椎小关节软骨成像的图像质量及特点。材料与方法前瞻性纳入健康受试者30例,均接受L4/L5~L5/S1的3.0 T MRI的腰椎常规序列(T1WI及T2WI序列)、三维快速扰相梯度回波水激励序列(water excitation three-dimensional spoiled gradient echo sequence,3D-WATSc)、基于T1加权的三维快速场回波(three-dimensional T1 fast field echo,3D-T1-FFE)、基于质子密度加权的三维各向同性快速自旋回波(three-dimensional proton density weighted imaging volumetric isotropic turbo spin echo acquisition,3D-PDWI-VISTA)序列扫描。对MRI图像进行成像效果的定性和定量评估。定性评估指标包括软骨的信号均匀性、软骨—关节间隙的边缘清晰度、软骨—骨的边缘锐度、软骨—关节间隙的对比度、软骨—骨的对比度;定量评估指标包括图像信噪比(signal to noise ratio,SNR)和对比噪声比(contrast to noise ratio,CNR)。结果3D-WATSc序列在5项定性评估指标中评分最高,3D-T1-FFE序列次之,仅软骨的信号均匀性指标在二者之间的差异具有统计学意义(P<0.05)。3D-PDWI-VISTA序列的5项定性指标评分均最差(P<0.05),且几乎不能分辨小关节的各层解剖结构,无法进行后续定量评估。3D-WATSc序列显示其软骨SNR[L4/L5(70.73±14.86)、L5/S1(73.50±13.63)]及软骨—关节间隙[L4/L5(25.30±8.44)、L5/S1(21.64±13.01)]、软骨—骨[L4/L5(60.75±14.68)、L5/S1(64.31±12.98)]、软骨—骨髓的CNR[L4/L5(50.22±14.33)、L5/S1(54.46±10.99)]均较3D-T1-FFE序列高,且差异具有统计学意义(P<0.05)。结论3.0 T MRI的3D-WATSc序列能够清晰地呈现腰椎小关节的软骨层及关节间隙,优于3D-T1-FFE及3D-PDWI-VISTA序列,对腰椎小关节软骨成像及腰椎小关节退变的临床诊断更具优势。Objective: To compare the image quality and imaging characteristics of three 3.0 T MRI sequences of lumbar facet joint cartilage.Materials and Methods: Thirty healthy subjects were studied with four chosen sequences using a 3.0 T MRI scanner. The sequences were T1WI/T2WI, water excitation three-dimensional spoiled gradient echo sequence(3D-WATSc), three-dimensional T1 fast field echo(3D-T1-FFE) and three-dimensional proton density weighted imaging volumetric isotropic turbo spin echo acquisition(3D-PDWI-VISTA).Two radiologists subjectively evaluated these MRI images qualitatively and quantitatively. Qualitative evaluation index including cartilage signal uniformity, cartilage-joint space edge sharpness, cartilage-bone edge sharpness, cartilage-joint space contrast, cartilage-bone contrast.Quantitative indicators include signal to noise ratio(SNR) and contrast to noise ratio(CNR). Results: The 3D-WATSc had the highest scores among the 5 qualitative indexes, and the 3D-T1-FFE had the second-highest scores. Only the difference of signal uniformity between the two was statistically significant(P<0.05). The 3D-PDWI-VISTA is almost indistinguishable from the anatomical structure of the lumbar facet joint. The 3D-WATSc showed that cartilage SNR [L4/L5(70.73±14.86), L5/S1(73.50±13.63)] and the CNR of cartilage-space [L4/L5(25.30±8.44), L5/S1(21.64±13.01)], cartilage-bone [L4/L5(60.75±14.68), L5/S1(64.31±12.98)], and cartilage-bone marrow [L4/L5(50.22±14.33), L5/S1(54.46±10.99)] were higher than that of 3D-T1-FFE, and the difference were statistically significant(P<0.05). Conclusions: The 3D-WATSc can present the anatomical structure of lumbar facet joints in detail,which is superior to 3D-T1-FFE and 3D-PDWI-VISTA. 3D-WATSc has advantage in imaging of lumbar facet joint cartilage and clinical diagnosis of lumbar facet joint degeneration.

关 键 词：磁共振成像 腰椎小关节 关节软骨 退行性变 成像序列 

分 类 号：R445.2[医药卫生—影像医学与核医学] R681.5[医药卫生—诊断学]