浮动均值法在C反应蛋白测定室内质控中的应用  

Application of the moving average method in the C-reactive protein indoor quality control

作　　者：王志勇[1] 张超[1] 李友建[1] 杨瑞锋[2] WANG Zhiyong;ZHANG Chao;LI Youjian;YANG Ruifeng(Department of Clinical Laboratory,Taixing People′s Hospital,Taixing,Jiangsu 225400,China;Peking University People′s Hospital/Institute of Hepatology Peking Universtery/Beijing Key Laboratory for Hepatitis C and Immunotherapy for Liver Diseases,Beijing 100044,China)

机构地区：[1]泰兴市人民医院检验科,江苏泰兴225400 [2]北京大学人民医院/北京大学肝病研究所/丙型肝炎和肝病免疫治疗北京市重点实验室,北京100044

出　　处：《国际检验医学杂志》2022年第16期2012-2014,2019,共4页International Journal of Laboratory Medicine

摘　　要：目的探讨浮动均值法在C反应蛋白(CRP)室内质控中的应用价值。方法从泰兴市人民医院实验室信息管理系统(LIS)中调取2020年所有患者的CRP检测数据作为浮动均值法计算对象。统计2020年5月和7月CRP检测数据每日均值,并绘制Levey-Jennings质控图,与质控物所绘制的质控图进行比较,统计2020年全年各月浮动均值法计算得到的靶值和标准差,观察浮动均值法应用于CRP质控的稳定性;结合国家卫生健康委临床检验中心和江苏省临床检验中心室间质评结果,评价浮动均值法发现“失控”结果的能力。结果与质控物所绘制的质控图比较显示,浮动均值法结果稳定,浮动均值法与质控物法所绘制的2020年5月质控图均显示在控,2020年7月室间质评不合格,检测当日质控物法显示室内质控在控,浮动均值法显示“失控”。结论浮动均值法具有一定的误差检出能力,结合质控物法进行室内质控可以有效提高误差发现能力。Objective To observe the application value of the moving average method in C-reactive protein(CRP)indoor quality control.Methods CRP test data of all patients in 2020 were collected from the laboratory Information Management System(LIS)of Taixing People′s Hospital as the calculation object of moving average method.The daily mean value of CRP test data in May and July of 2020 was counted,the Levey-Jennings quality control chart was drawn,and compared with the quality control chart drawn by routine quality control.The target value and standard deviation calculated by the moving average method for each month of 2020 were counted,and the stability of the moving average method applied to CRP quality control was observed.The ability of moving average method to detect"out-of-control"results was evaluated based on the results of laboratory quality assessment in the Clinical Laboratory Center of National Health Commission and Jiangsu Center for Clinical Laboratories.Results Compared with the quality control chart drawn by quality control materials,the result of moving average method was stable.The quality control chart drawn by moving average method and quality control materials method in May 2020 was under control,but the indoor quality assessment in July 2020 was unqualified.The quality control materials method on the test day showed that the indoor quality control was under control,and the moving average method showed"out-of-control".Conclusion The moving average method has a certain error detection ability.Combined with the quality control method for indoor quality control could effectively improve the error detection ability.

关 键 词：浮动均值法 C反应蛋白 质量控制 

分 类 号：R446.1[医药卫生—诊断学]