血气分析指标在妊娠高血压综合征患者病情评估中的作用  

Role of blood gas analysis indexes in condition assessment of patients with pregnancy-induced hypertension syndrome

作　　者：陈璐 张西艺 李维玲[1] 陈媛媛[1] 王岐山[2] CHEN Lu;ZHANG Xiyi;LI Weiling;CHEN Yuanyuan;WANG Qishan(Xi'an Gaoxin Hospital,Xi'an 710075;Shaanxi Provincial People's Hospital,Xi'an 710068,China)

机构地区：[1]西安高新医院,陕西西安710075 [2]陕西省人民医院,陕西西安710068

出　　处：《临床医学研究与实践》2022年第25期17-20,共4页Clinical Research and Practice

基　　金：陕西省社会发展科技攻关项目(No.2015SF135)。

摘　　要：目的分析妊娠高血压综合征患者的血气分析指标及新生儿Apgar评分,以期指导病情评估。方法选取2017年3月至2021年3月我院收治的412例妊娠高血压综合征患者作为研究组,同时选取同期189名健康孕妇作为对照组。将研究组根据疾病严重程度分为轻度组(n=256)、中度组(n=86)、重度组(n=70)。收集研究组和对照组的一般资料,测定血气分析指标,记录Apgar评分。比较研究组和对照组的一般资料;比较研究组不同亚组的一般资料;比较研究组不同亚组和对照组的血气分析指标、Apgar评分;分析研究组不同亚组pH与Apgar评分的相关性。结果研究组和对照组的年龄、生育情况、分娩方式、居住地、总蛋白(TP)、白蛋白(ALB)水平、新生儿性别、胎龄、新生儿体重比较,差异无统计学意义(P>0.05)。轻度组、中度组、重度组的年龄、生育情况、分娩方式、居住地、TP、ALB水平、新生儿性别、胎龄、新生儿体重比较,差异无统计学意义(P>0.05)。轻度组、中度组、重度组的pH、氧分压(PO_(2))、HCO_(3)^(-)水平、Apgar评分低于对照组,二氧化碳分压(PCO_(2))、碱剩余(BE)水平高于对照组,差异具有统计学意义(P<0.05);中度组、重度组的pH、PO_(2)、HCO_(3)^(-)水平、Apgar评分低于轻度组,PCO_(2)、BE水平高于轻度组,差异具有统计学意义(P<0.05);重度组的pH、PO_(2)、HCO_(3)^(-)水平、Apgar评分低于中度组,PCO_(2)、BE水平高于中度组,差异具有统计学意义(P<0.05)。研究组不同亚组pH与Apgar评分均呈正相关(P<0.05)。结论血气分析指标在一定程度上有助于评估妊娠高血压综合征患者的病情,结合Apgar评分有助于判断新生儿窒息情况。Objective To analyze the blood gas analysis indexes of patients with pregnancy-induced hypertension syndrome and neonatal Apgar score,so as to guide the condition assessment.Methods A total of 412 patients with pregnancy-induced hypertension syndrome treated in our hospital from March 2017 to March 2021 were selected as study group,and 189 healthy pregnant women in the same period were selected as control group.The study group was divided into mild group(n=256),moderate group(n=86)and severe group(n=70)according to the severity of disease.The general data of the study group and the control group were collected,the blood gas analysis indexes were measured,and the Apgar score was recorded.The general data of the study group and the control group were compared;the general data of different subgroups of the study group were compared;the blood gas analysis indexes and Apgar score of different subgroups of the study group and the control group were compared;the correlation between pH and Apgar score in different subgroups of the study group was analyzed.Results There were no significant differences in age,fertility condition,delivery method,residence,total protein(TP)and albumin(ALB)levels,neonatal gender,gestational age and neonatal weight between the study group and the control group(P>0.05).There were no significant differences in age,fertility condition,delivery method,residence,TP and ALB levels,neonatal gender,gestational age and neonatal weight among the mild group,the moderate group and the severe group(P>0.05).The pH,partial pressure of oxygen(PO_(2)),HCO_(3)^(-) level and Apgar score of the mild group,the moderate group and the severe group were lower than those of the control group,while the partial pressure of carbon dioxide(PCO_(2))and base excess(BE)level were higher than those of the control group,and the differences were statistically significant(P<0.05);the pH,PO_(2),HCO_(3)^(-) level and Apgar score of the moderate group and the severe group were lower than those of the mild group,while the PCO_(2) an

关 键 词：妊娠高血压综合征 血气分析指标 APGAR评分 

分 类 号：R722.1[医药卫生—儿科]