分析胺碘酮治疗顽固性室性心动过速和心室颤动的临床疗效  

Clinical efficacy of amiodarone in the treatment of refractory ventricular tachycardia and ventricular fibrillation

作　　者：王学强 WANG Xue-qiang(Senior Medical Officer,Beipiao Central Hospital,Beipiao 122100,China)

机构地区：[1]辽宁省北票市中心医院老年医学科,122100

出　　处：《中国实用医药》2022年第17期110-112,共3页China Practical Medicine

摘　　要：目的 分析胺碘酮治疗顽固性室性心动过速和心室颤动的临床疗效。方法 18例顽固性室性心动过速和心室颤动患者作为观察对象,所有患者复发均使用利多卡因及除颤治疗无法对其维持窦性心律,之后均予以胺碘酮治疗。分析患者心律失常控制情况、胺碘酮用药情况及随访结果。结果 所有患者在治疗72 h内心律失常现象均完全控制。随访过程中发现, 1例患者在治疗18 d后自行停止了胺碘酮用药,在治疗28 d后再次突发性出现室性心动过速,给予除颤治疗无效,最终抢救失败发生死亡。其余17例患者在病情得到控制后,保持胺碘酮的长期口服治疗,均未发生再次复发现象。结论 胺碘酮对顽固性室性心动过速和心室颤动有着良好的治疗效果,需要长期服用治疗,在治疗过程中需要注意对患者各项生命体征的监测,值得临床推广应用。Objective To analyze the clinical efficacy of amiodarone in the treatment of refractory ventricular tachycardia and ventricular fibrillation.Methods 18 patients with refractory ventricular tachycardia and ventricular fibrillation were selected as the observation subjects.All patients who relapsed were unable to maintain sinus rhythm with lidocaine and defibrillation,and were then treated with amiodarone.The control of arrhythmia,the use of amiodarone and the follow-up results of the patients were analyzed.Results Arrhythmias in all patients were completely controlled within 72 h of treatment.During the follow-up,1 patient who stopped amiodarone administration after 18 d of treatment suddenly developed ventricular tachycardia again after 28 d of treatment and died after treatment with defibrillation was ineffective and resuscitation failed.The remaining 17 patients maintained long-term oral treatment with amiodarone after their condition was controlled,and no relapse occurred.Conclusion Amiodarone has good therapeutic effect on refractory ventricular tachycardia and ventricular fibrillation,but it needs to be taken for a long period of time and the monitoring of patients'vital signs should be paid attention to during the treatment,which is worthy of clinical promotion and application.

关 键 词：胺碘酮 顽固性室性心动过速 心室颤动 临床疗效 

分 类 号：R541.7[医药卫生—心血管疾病]