特发性羊水过多的妊娠结局和新生儿性别组成探讨  

Pregnancy outcomes and neonatal gender in idiopathic polyhydramnios

作　　者：李玲[1] 易慧[1] 李陈 朱娟[1] 魏然[1] LI Ling;YI Hui;LI Chen;ZHU Juan;WEI Ran(Medical Genetic Center,Guangdong Women and Children Hospital,Guangzhou 510010,China)

机构地区：[1]广东省妇幼保健院医学遗传中心,广州510010

出　　处：《妇产与遗传（电子版）》2022年第1期14-17,共4页Obstetrics-Gynecology and Genetics (Electronic Edition)

摘　　要：目的探讨特发性羊水过多的妊娠结局及新生儿性别组成。方法选取2016年1月至2020年12月在广东省妇幼保健行Ⅲ级超声诊断和产前诊断中心诊断为特发性羊水过多并性介入性诊断的单胎病例102例为研究组,所有妊娠结局及新生儿性别通过随访获得;选取同期因夫妻双方地中海贫血基因携带在广东省妇幼保健院医学遗传中心行产前诊断的正常胎儿2980例为对照组。结果研究组较对照组的早产率(11.76%vs 3.62%)、剖宫产率(41.17%vs 30.80%)、巨大儿出生率(9.80%vs 2.52%)、男性新生儿比例(68.62%vs 54.96%)均较高,差异有统计学意义(P<0.05);研究组与对照组低体重儿出生率分别为7.84%与5.13%,差异无统计学意义(P>0.05)。结论特发性羊水过多会增加早产、剖宫产及巨大儿的风险,但不会增加低体重儿的风险。特发性羊水过多中男性新生儿的比例较高。Objective To explore the outcome and neonatal gender of pregnancy in women diagnosed with idiopathic polyhydramnios.Methods From January 2016 to December 2020,102 singleton pregnancies of idiopathic polyhydramnios diagnosed byⅢultrasound in medical genetic center of Guangdong Women and Children Hospital were selected as the study group.All obstetric outcomes and neonatal gender were obtained by follow-up;2980 normal fetuses diagnosed in medical genetic center of Guangdong Women and Children Hospital due to parents with thalassemia during the same period as the control group.Results Compared with the control group,the preterm birth rate(11.76%vs 3.62%),the cesarean section rate(41.17%vs 30.80%),the macrosomia birth rate(9.80%vs 2.52%),the proportion of male newborns(68.62%vs 54.96%)in the study group were higher(P<0.05)and the difference was statistically significant.The birth rate of low birth weight infants between the study group and the control group was 7.84%and 5.13%,and the difference was not statistically significant(P>0.05).Conclusions Idiopathic polyhydramnios increases the risk of specific adverse outcomes,such as higher rate of preterm delivery,caesarean delivery and macrosomia,but not low birth weight.The proportion of male neonate is higher in idiopathic polyhydramnios.

关 键 词：羊水过多 妊娠结局 婴儿 新生儿 

分 类 号：R714.2[医药卫生—妇产科学]