经皮冠状动脉介入术治疗老年冠脉慢性完全闭塞致稳定性心绞痛的临床疗效  

Clinical efficacy of percutaneous coronary intervention in the treatment of stable angina pectoris caused by chronic total coronary occlusion in elderly patients

作　　者：李云峰 聂恒浩[1] 胡荣鑫 LI Yunfeng;NIE Henghao;HU Rongxin(Department of Cardiology,Shenyang Second Hospital of Traditional Chinese Medicine,Shenyang,Liaoning,110101,China)

机构地区：[1]沈阳市第二中医医院心内科,辽宁沈阳110101

出　　处：《当代医学》2022年第16期113-116,共4页Contemporary Medicine

摘　　要：目的探讨经皮冠状动脉介入术(PCI)治疗老年冠脉慢性完全闭塞(CTO)致稳定性心绞痛(SA)的临床疗效。方法回顾性分析2019年1月至2021年6月本院收治的108例CTO致SA患者的临床资料,按电脑双色球随机法分为两组,各54例。对照组给予常规抗心绞痛药物治疗,观察组在对照组基础上联合PCI治疗。比较两组治疗后症状恢复情况、心功能及不良心血管事件发生情况。结果治疗后,观察组心绞痛发作频率低于对照组,持续时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。治疗前,两组左室舒张末期容积(LVEDV)、左室收缩末期容积(LVESV)、左室射血分数(LVEF)比较差异无统计学意义;治疗后,观察组LVEDV、LVESV水平均低于对照组,LVEF高于对照组,差异有统计学意义(P<0.05)。治疗后6个月,两组不良心血管事件发生率比较差异无统计学意义。结论PCI治疗老年CTO致SA具有一定临床疗效,可改善患者心功能,减轻心绞痛症状,值得临床推广应用。Objective To investigate the clinical efficacy of percutaneous coronary intervention(PCI)in the treatment of stable angina(SA)caused by chronic total coronary occlusion(CTO)in elderly patients.Methods The clinical data of 108 CTO induced SA patients admitted to our hospital from January 2019 to June 2021 were retrospectively analyzed,and they were divided into two groups according to the computerized twocolor ball randomization method,with 54 cases in each group.The control group was treated with conventional anti-angina pectoris drugs,and the observation group was treated with PCI on the basis of the control group.The symptom recovery,cardiac function and adverse cardiovascular events were compared between the two groups after treatment.Results After treatment,the frequency of angina pectoris attacks in the observation group was lower than that in the control group,and the duration and hospital stay were shorter than those in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV)and left ventricular ejection fraction(LVEF)between the two groups;after treatment,the levels of LVEDV and LVESV in the observation group were lower than those in the control group,and the level of LVEF was higher than that in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse cardiovascular events between the two groups during the 6-month follow-up after treatment.Conclusion PCI has certain clinical effect in the treatment of elderly CTO complicated with SA,which can improve the cardiac function and relieve the symptoms of angina pectoris,which is worthy of clinical application.

关 键 词：冠脉慢性完全闭塞 稳定性心绞痛 经皮冠状动脉介入术 心功能 不良心血管事件 

分 类 号：R541.4[医药卫生—心血管疾病]