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作 者:陈张好[1] CHEN Zhanghao(CFDA Key Laboratory of Cosmetics Safety Risk Assesment/Guangdong Institute for Drug Control,Guangzhou 510663,Guangdong,China)
机构地区:[1]广东省药品检验所/国家药监局化妆品风险评估重点实验室,广东广州510663
出 处:《香料香精化妆品》2022年第4期26-31,共6页Flavour Fragrance Cosmetics
基 金:广东省药品监督管理局科技创新重点实验室专项(编号2021ZDZ03)。
摘 要:为了解化妆品中二乙醇酰胺类原料的使用情况及安全评估状况,确保消费者使用安全的化妆品,分别对国产及进口的656批淋洗类化妆品中二乙醇酰胺类原料的使用情况进行统计分析,并总结了该类物质的安全评估状况及相关国内外管理法规要求。该类原料在淋洗类化妆品中使用频率较高(23.8%),在国产产品中的使用频率(33.7%)远高于进口产品(12.8%)。该类原料在一定条件下可能形成N-亚硝胺类化合物,使用频率最高的椰油酰胺DEA被列入美国加州65号清单,存在一定的安全风险。建议进一步关注该类原料的使用安全。To know the usage and safety evaluation of diethanolamides(DEAs)in cosmetics,and to ensure cosmetic products being safe for consumers,the usage of DEAs in 656 batches of domestic and imported washing cosmetics was analyzed statistically,and the safety evaluation status and management regulations at home and abroad were summarized.The results showed that DEAs were frequently used in washing cosmetics(23.8%).The use frequency in domestic products(33.7%)was much higher than that in imported products(12.8%).Since DEAs may form N-nitrosamines in some conditions,and the cocamide DEA,which is the most frequently used,has been listed in Chemicals Known to the State to Cause Cancer or Reproductive Toxicity by California Environmental Protection Agency.There are certain safety risks.It’s necessary to pay more attention to the safety risks of DEAs.
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