病毒性心肌炎患儿体内氧化应激和窦房结内游走性节律研究  

The study on the oxidative stress level and sinoatrial node migratory rhythm in children with viral myocarditis

作　　者：郭丹羽 李堰松[1] Guo Danyu;Li Yansong(Shiyan maternal and child health care hospital,Shiyan 442000,China)

机构地区：[1]十堰市妇幼保健院,湖北十堰442000

出　　处：《现代科学仪器》2022年第4期113-117,共5页Modern Scientific Instruments

摘　　要：目的:探讨病毒性心肌炎患儿体内氧化应激水平和窦房结内游走性节律。方法:选取50例病毒性心肌炎患儿(患病组)和同期50例健康体检儿童(对照组)作为研究对象。检测两组血浆一氧化氮(NO)、血浆及红细胞中过氧化脂质(LPO)含量及血浆GST和红细胞中CAT活性,记录心电图特征。结果:患病组血浆NO、血浆及红细胞中LPO高于对照组,血浆GST活性和红细胞中CAT活性低于对照组(P<0.05)。患病组3例出现窦房结内游走性心律。结论:病毒性心肌炎患儿体内氧化应激水平增加,部分伴随窦房结内游走性心律。Objective:To investigate the level of oxidative stress and wandering rhythm in sinoatrial node in children with viral myocarditis..Methods:50 children with viral myocarditis(disease group)and 50 healthy children with physical examination at the same period(control group)were selected as the research objects..The contents of plasma nitric oxide(NO),lipid peroxide(LPO)in plasma and red blood cells and the activity of plasma GST and CAT in red blood cells were determined,the ECG characteristics were recorded.Results:The levels of plasma NO,the LPO in plasma and red blood cells in the patients were significantly higher than those in the control group,the activity of GST in plasma and CAT in red blood cells were significantly lower than that in control group(P<0.05).There were 3 cases of sinus node wandering rhythm in the group.Conclusion:The level of oxidative stress in children with viral myocarditis was increased,and some of them were accompanied by a wandering sinus node rhythm..

关 键 词：病毒性心肌炎 氧化应激 窦房结内游走性节律 

分 类 号：R287.6[医药卫生—中药学]