无溶剂条件下合成苯并吡喃类衍生物  

Synthesis of Chromene Derivatives under Free Solvent

作　　者：李艳春[1] 周天宇 LI Yan-chun;ZHOU Tian-yu(College of Chemistry and Chemical Engineering,Longdong University,Qingyang 745000,Gansu;Primary School of Nanhu,Pingliang 744603,Gansu)

机构地区：[1]陇东学院化学化工学院,甘肃庆阳745000 [2]南湖小学,甘肃平凉744603

出　　处：《陇东学院学报》2022年第5期76-79,共4页Journal of Longdong University

基　　金：西峰区科技计划(XK2018-16);甘肃省高等学校创新能力提升(2019B-159);甘肃省高等学校科研项目创新团队资助项目(2018C-22);甘肃省自然科学基金(21JR1RM335)。

摘　　要：以Na_(2)CO_(3)为催化剂,采用无溶剂“一锅法”合成了5个苯并色烯衍生物,收率为79.6%~94.4%。以苯甲醛、丙二腈和间苯二酚为模板反应,通过单因素试验优化了反应条件。该法具有操作及后处理简单、反应时间短及环境友好等优点。Using Na_(2)CO_(3) as catalyst,five chromene derivatives were synthesized by one-pot under free solvent in yields of 79.6%-94.4%.With benzaldehyde,malononitrile,and resorcinol as template reaction,the reaction conditions were optimized by single factor experiments.This protocol has the merits of simple operation,convenient work-up and short reaction time and environmentally benign.

关 键 词：Na_(2)CO_(3) 苯并吡喃 无溶剂 环境友好 

分 类 号：O626.3[理学—有机化学]