Genomic insights into versatile lifestyle of three new bacterial candidate phyla  

作　　者：Xinxu Zhang Zongbao Liu Wei Xu Jie Pan Yuhan Huang Mingwei Cai Zhuhua Luo Meng Li 

机构地区：[1]Archaeal Biology Center,Institute for Advanced Study,Shenzhen University,Shenzhen 518060,China [2]Shenzhen Key Laboratory of Marine Microbiome Engineering,Institute for Advanced Study,Shenzhen University,Shenzhen 518060,China [3]Key Laboratory of Marine Biogenetic Resources,Third Institute of Oceanography,Ministry of Natural Resources,Xiamen 361005,China [4]School of Marine Sciences,Nanjing University of Information Science&Technology,Nanjing 210044,China

出　　处：《Science China(Life Sciences)》2022年第8期1547-1562,共16页中国科学（生命科学英文版）

基　　金：supported by the National Natural Science Foundation of China(91951102,31800105,31970105,32061133009);the Innovation Team Project of Universities in Guangdong Province(2020KCXTD023);the Scientific Research Foundation of Third Institute of Oceanography,MNR(2019022);the Science and Technology Innovation Committee of Shenzhen(JCYJ20190808152403587,JCYJ20180305163524811,JCYJ20200109105010363)。

摘　　要：Metagenomic explorations of the Earth's biosphere enable the discovery of previously unknown bacterial lineages of phylogenetic and ecological significance.Here,we retrieved 11 metagenomic-assembled genomes(MAGs)affiliated to three new monophyletic bacterial lineages from the seawater of the Yap Trench.Phylogenomic analysis revealed that each lineage is a new bacterial candidate phylum,subsequently named Candidatus Qinglongiota,Candidatus Heilongiota,and Candidatus Canglongiota.Metabolic reconstruction of genomes from the three phyla suggested that they adopt a versatile lifestyle,with the potential to utilize various types of sugars,proteins,and/or short-chain fatty acids through anaerobic pathways.This was further confirmed by a global distribution map of the three phyla,indicating a preference for oxygen-limited or particle-attached niches,such as anoxic sedimentary environments.Of note,Candidatus Canglongiota genomes harbor genes for the complete WoodLjungdahl pathway and sulfate reduction that are similar to those identified in some sulfate-reducing bacteria.Evolutionary analysis indicated that gene gain and loss events,and horizontal gene transfer(HGT)play important roles in shaping the genomic and metabolic features of the three new phyla.This study presents the genomic insight into the ecology,metabolism,and evolution of three new phyla,which broadens the phylum-level diversity within the domain Bacteria.

关 键 词：METAGENOMICS horizontal gene transfer FERMENTATION anaerobic respiration evolution marine habitat 

分 类 号：Q933[生物学—微生物学]