中医针刺疗法治疗伴有顽固性幻听慢性精神分裂症患者功能康复多中心随机对照研究  

Functional Rehabilitation of Chronic Schizophrenia Patients with Refractory Auditory Hallucinations Treated with Acupuncture: A Multicentre Randomized Controlled Trial

作　　者：崔界峰[1] 王绍礼[1] 赵霞[1] 郑军然 闫少校[1] CUI Jie-feng;WANG Shao-li;ZHAO Xia;ZHENG Jun-ran;YAN Shao-xiao(Beijing Psychiatric Institution of Integrated Traditional and Western Medicine,Beijing Huilongguan Hospital,Beijing,100096)

机构地区：[1]北京回龙观医院中西医结合精神医学研究所,北京100096

出　　处：《中国中西医结合杂志》2022年第7期817-821,共5页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：北京市首都卫生发展科研专项项目(No.首发2016-1-2132);国家中医药管理局岐黄学者项目(No.2019)。

摘　　要：目的 评估中医针刺疗法对伴有顽固性幻听慢性精神分裂症患者功能康复的影响。方法 来自北京回龙观医院、朝阳三院和密云区精神卫生防治院的精神分裂症患者114例,采用随机区组法入组,分为针疗组76例和对照组38例。针疗组接受抗精神病药联合针刺治疗;对照组仅接受抗精神病药治疗,共持续12周。采用精神分裂症认知功能成套测验(MCCB)评估认知功能;采用自编中医情绪调查表(TCMEQ)评估中医情绪相关症状;采用个人和社会功能量表(PSP)评估患者社会康复功能的程度;采用精神分裂症生活质量量表(SQLS)评估患者的生活质量。结果 针疗组治疗后MCCB总分、连线A(TMT)、符号编码测验(SC)、持续操作测验(CPT-IP)、TCMEQ次症分、PSP和SQLS较治疗前改善(P<0.05),对照组治疗后MCCB各认知功能指标、TCMEQ次症分、PSP和SQLS较治疗前无改善(P>0.05),两组治疗后比较差异有统计学意义(P<0.05)。结论 中医针刺疗法治疗伴有顽固性幻听慢性精神分裂症患者,可以提高其社会康复功能,改善其生活质量,对某些认知功能有改善作用。Objective To evaluate the effect of acupuncture on functional rehabilitation in patients with chronic schizophrenia with refractory auditory hallucinations. Methods Totally 114 patients with schizophrenia enrolled method from Beijing Huilongguan Hospital, Chaoyang Third Hospital, and Miyun District Mental Health Hospital for Prevention and Treatment were assigned to the acupuncture group(76 cases) and the control group(38 cases) by random block method. Patients in the acupuncture group received acupuncture and antipsychotics, while those in the control group received antipsychotics alone. The treatment course lasted for 12 weeks. Cognitive function was assessed by the MATRICS Consensus Cognitive Battery(MCCB). Traditional Chinese Medicine Emotional Questionnaire(TCMEQ) was used to evaluate TCM emotional symptoms. The Personal and Social Performance Scale(PSP) was used to assess the degree of social rehabilitation. The Schizophrenia Quality of Life Scale(SQLS) was used to evaluate the quality of life of the patients. Results In the acupuncture group, the total score of MCCB, trail-making test(TMT), symbol coding test(SC), and continuous performance testidentical pairing(CPT-IP), TCMEQ secondary syndrome, PSP and SQLS showed significant differences between before and after treatment(P<0.05). In the control group, all subtests and total score of MCCB, TCMEQ secondary syndrome, PSP and SQLS showed no significant differences between before and after treatment(P>0.05). There were significant differences in post-treatment changes between the acupuncture group and the control group(P<0.05). Conclusions Acupuncture had obvious effects on chronic schizophrenia patients with refractory auditory hallucinations, improved their social function, improved their quality of life, and promoted some cognitive dimensions.

关 键 词：精神分裂症 顽固性幻听 中医针刺疗法 认知功能 社会功能 生活质量 

分 类 号：R246.6[医药卫生—针灸推拿学]