Synthesis and Antibacterial Properties of ZIF-8/Ag-Modified Titanium Alloy  

作　　者：Mingrui Li Yongjie Wei Bowen Ma Yang Hu Dongdong Li Xiaoqiang Cui 

机构地区：[1]Key Laboratory of Automobile Materials of MOE,Department of Materials Science and Engineering,Jilin University,Changchun 130022,China [2]State Key Laboratory for Materials Processing and Die and Mould Technology,School of Materials Science and Engineering,Huazhong University of Science and Technology,Wuhan 430074,China

出　　处：《Journal of Bionic Engineering》2022年第2期507-515,共9页仿生工程学报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.51627805).

摘　　要：The loosening of implant due to bacterial infection brings great difficulties to the implantation of bionic titanium devices.In this study,the Zeolitic Imidazolate Framework 8(ZIF-8)and silver ions were added to the surface of titanium alloy to obtain a uniform coating,which has nice biological activity and antibacterial property.The material structure characterizations,such as X-ray diffraction(XRD),scanning electron microscope(SEM),X-ray photoelectron spectroscopy(XPS),proved that titanium is successfully modified with ZIF-8 and silver ions.It has micro-and nano-level characteristics,rough porous morphology,and excellent apatite inducing ability.The water contact angle experiment shows that the addition of ZIF-8 greatly increases the hydrophilicity of material,which provides conditions for the attachment of osteoblasts.The polarization curve obtained from the electrochemical test proves that the addition of ZIF-8 coating improves the corrosion resistance of titanium.The release of silver ion has a strong growth inhibitory effect on E.coli,and exhibits excellent antibacterial properties.Therefore,the preparation of ZIF-8/Ag coatings on 3D printed titanium provides a new option for the development of orthopedic implants.

关 键 词：Zeolitic imidazolate framework-8 ANTIBACTERIAL OSSEOINTEGRATION Surface modifcatio 

分 类 号：TG146.23[一般工业技术—材料科学与工程]