缩宫素在剖宫产手术中防治产后出血的量效学研究及影响产后出血预防效果的回归分析  

Quantitative and effect study of oxytocin in prevention and treatment of postpartum hemorrhage during cesarean section and Logistic regression analysis affecting the preventive effect of postpartum hemorrhage

作　　者：张喜罗 ZHANG Xi-luo(Linying County People’s Hospital,Linying,Henan 462600,China)

机构地区：[1]临颍县人民医院妇产科,河南临颍462600

出　　处：《医药论坛杂志》2022年第12期54-57,共4页Journal of Medical Forum

摘　　要：目的研究缩宫素预防产后出血、加速产后子宫恢复的效果及产妇产后出血的影响因素。方法选取2019年11月—2021年10月临颍县人民医院收治的剖宫产孕妇80例,按照随机数字表法分为观察组和对照组,每组40例。比较两组产妇出血量及子宫复旧情况。根据产后是否出现产后出血将产妇分为出血组和非出血组,采用单因素及多因素logistics回归分析研究影响产妇剖宫产产后出血的影响因素。结果产后2小时、产后12小时、产后24小时,观察者产妇产后出血量均显著低于对照组(P<0.05)。随着产后时间的延长,两组产妇子宫均逐渐下降,观察者产后第3天及产后第5天的子宫高度显著低于对照组(P<0.05)。80例剖宫产产妇中,有30(37.50%)例产妇初选产后出血,50(62.50%)例产妇非产后出血。妊娠期糖尿病、妊娠期高血压、流产史为产妇剖宫产术后出血的独立危险因素。结论对于剖宫产手术,相比较于子宫体肌注20单位缩宫素联合10单位缩宫素静脉滴注,采用静脉滴注20单位缩宫素更加有利于产后子宫恢复,降低产后出血。妊娠期糖尿病、妊娠期高血压、流产史的产妇产后出血风险大。Objective To study the effect of oxytocin in preventing postpartum bleeding and accelerating postpartum u⁃terine recovery and the influencing factors of maternal postpartum bleeding.Methods A total of 80 pregnant women with cesarean section admitted to our hospital from November 2019 to October 2021 were selected and divided into observation and control groups according to the randomized digital tables,with 40 cases in each group.The amount of maternal bleeding and uterine recovery were compared between the two groups.Women were divided into bleeding and unbleeding groups according to whether postpartum bleeding occurred,and unifactors and multivariate logistics regression analysis were used to study the influencing factors affecting postpartum bleeding by cesarean section.Results At 2 hours post⁃partum,12 hours postpartum and 24 hours postpartum,the observer maternal postpartum bleeding was significantly lower than that of the control group(P<0.05).With the longer postpartum time,both groups gradually declined,and the u⁃terine height was significantly lower on day 3 and 5 postpartum than in the control group(P<0.05).Of the 80 women with cesarean sections,30(28.99%)of women had primary postpartum bleeding,and 50(69.57%)of women had no postpartum bleeding.Gestational diabetes,gestational hypertension,and history of abortion were independent risk factors for maternal bleeding after cesarean section.Conclusion For cesarean section,compared with 20 units of condensin combined with 10 units of hysterosin intravenous infusion,intravenous infusion of 20 units of condensin is more condu⁃cive to postpartum uterine recovery,reduce postpartum bleeding,postpartum bleeding in the history of gestational diabe⁃tes,gestational hypertension and abortion.

关 键 词：缩宫素 剖宫产手术 产后出血 效果 LOGISTIC回归分析 

分 类 号：R714.461[医药卫生—妇产科学]