十一方药酒的体外抑菌作用研究  

Study on Antibacterial Effect of Shiyifang Vinum in Vitro

作　　者：刘舒凌[1] 黄娟[1] 唐杰 陈宏夏 张超裕 屈泽强[1] Liu Shuling;Huang Juan;Tang Jie;Chen Hongxia;Zhang Chaoyu;Qu Zeqiang(Guangxi University of Chinese Medicine,Nanning 530200,China;Guangxi Academy of Agricultural Sciences,Nanning 530007,China)

机构地区：[1]广西中医药大学,广西南宁530200 [2]广西农业科学院,广西南宁530007

出　　处：《亚太传统医药》2022年第8期44-48,共5页Asia-Pacific Traditional Medicine

基　　金：广西壮族自治区科技厅广西创新驱动发展专项资金项目(桂科AA17202036);广西壮族自治区中医药管理局中药壮瑶药医院制剂质量提升项目(GZZJ202001)。

摘　　要：目的:研究十一方药酒的体外抑菌作用。方法:采用琼脂稀释法和试管二倍稀释法,测定十一方药酒对金黄色葡萄球菌、铜绿假单胞菌、白色念珠菌、乙型副伤寒沙门菌、表皮葡萄球菌的最低抑菌浓度(MIC)和最低杀菌浓度(MBC)。结果:琼脂稀释法显示十一方药酒对金黄色葡萄球菌的MIC为6.0313mg/mL,对铜绿假单胞菌、白色念珠菌、乙型副伤寒沙门菌、表皮葡萄球菌的MIC为12.0625mg/mL。试管二倍稀释法显示十一方药酒对金黄色葡萄球菌、铜绿假单胞菌、白色念珠菌、乙型副伤寒沙门菌、表皮葡萄球菌的MBC为12.0625mg/mL。结论:十一方药酒对供试菌均具有体外抑菌作用。Objective:To study the antibacterial effect of Shiyifang Vinum in vitro.Methods:Minimum inhibitory concentration(MIC)and minimum bactericidal concentration(MBC)of Shiyifang Vinum against Staphylococcus aureus,Pseudomonas aeruginosa,Candida albicans,Salmonellapara-typhi B and Staph ylococcus epidermidis were determined by Agar dilution method and test tube double dilution method.Results:Agar dilution method showed that the MIC of Shiyifang Vinum was 6.0313 mg/mL against Staphylococcus aureus,and 12.0625 mg/mL against Pseudomonas aeruginosa,Candida albicans,Salmonellapara-typhi B and Staphylococcus epidermidis.The test tube double dilution method showed that the MBC of Shiyifang Vinum against Staphylococcus aureus,Pseudomonas aeruginosa,Candida albicans,Salmonellapara-typhi B and Staphylococcus epidermidis was 12.0625 mg/mL.Conclusion:Shiyifang Vinum had antibacterial effect on the tested bacteria in vitro.

关 键 词：十一方药酒 体外抑菌 最低抑菌浓度 最低杀菌浓度 

分 类 号：R285.5[医药卫生—中药学]