基于脉搏波传播速度的动脉僵硬度超声自动测量新方法  

New method for automatic measurement of arterial stiffness by Doppler ultrasound derived pulse wave velocity

作　　者：杨勇 梁潇 杜京奚 曹铁生 王臻 Yang Yong;Liang Xiao;Du Jingxi;Cao Tiesheng;Wang Zhen(Department of Ultrasound Medicine,the Second Affiliated Hospital of Airforce Military Medical University,Xi′an 710038,China;School of Aerospace Medicine,Airforce Military Medical University,Xi′an 710032,China)

机构地区：[1]空军军医大学第二附属医院超声医学科,西安710038 [2]空军军医大学航空航天医学系,西安710032

出　　处：《中华超声影像学杂志》2022年第7期579-584,共6页Chinese Journal of Ultrasonography

基　　金：国家自然科学基金(81801865);空军军医大学第二附属医院临床研究项目(2021LCYJ030)。

摘　　要：目的探究一种基于区段脉搏波传播速度(pulse wave velocity,PWV)测量的动脉僵硬度超声自动测量新方法——AMAS(automatic measurement of arterial stiffness)系统的准确性及可重复性。方法纳入2019年9月1-30日在空军军医大学唐都医院心内科住院的高血压患者30例作为高血压组,招募同期健康者30例作为健康组。由两名独立观察者分别采用传统手动法和AMAS系统对60例受检者的颈-股PWV进行测量并对比分析两种方法测值的一致性。结果经AMAS系统自动测量的颈-股PWV与传统手动法测值间差异无统计学意义(P>0.05),且两者间的组内相关系数为0.953(95%CI=0.922~0.971),Bland-Altman分析亦显示两种方法具有高度的一致性[差值均值:-(0.08±0.40)m/s;一致性界限:-0.87~0.71 m/s]。AMAS系统较传统手动法可节省约70%的测量时间且具有较高的可重复性。结论AMAS系统测量动脉僵硬度具有较好的准确性和可重复性,可为临床提供一种无创、快速、可靠的动脉僵硬度评价方法。Objective To investigate the accuracy and reproducibility of a new method,Automatic Measurement of Arterial Stiffness(AMAS)system,for arterial stiffness automatic measurement based on regional pulse wave velocity(PWV).Methods A total of 30 hypertensive patients who were hospitalized in the Department of Cardiology in Tangdu Hospital,Air Force Military Medical University from September 1 to 30,2019 were enrolled as hypertensive group,while 30 healthy participants at the same time were collected as healthy group.Carotid-femoral PWV(cfPWV)was measured in all subjects by two independent observers using the conventional manual method and the AMAS system.The measurements were compared and the agreement was analyzed.Results There was no significant difference of cfPWV between AMAS system and the manual method,and the intraclass correlation coefficient was 0.953(95%CI=0.922-0.971).Bland-Altman plots showed good agreement[mean difference:-(0.08±0.40)m/s;limit of agreement:-0.87-0.71 m/s].Time consumption for cfPWV measurement using the AMAS system was significantly less than that of conventional manual method,saving about 70%of the time.The cfPWV measured by AMAS showed good intra-and inter-observer reproducibility.Conclusions AMAS system is accurate and reproducible in measuring arterial stiffness.It may provide a noninvasive,rapid,reliable approach for arterial stiffness evaluation in clinical settings.

关 键 词：超声检查 脉搏波传播速度 动脉僵硬度 自动测量 动脉硬化 

分 类 号：R445.1[医药卫生—影像医学与核医学]