Bakuchiol and astaxanthin:a new weapon for sun protection?  

作　　者：Domina Petric 

机构地区：[1]Department of Clinical pharmacology and toxicology,University Hospital Center Split,Split,Croatia.

出　　处：《Food and Health》2022年第3期15-17,共3页食品和健康（英文）

摘　　要：Exposure to sunlight must be very well balanced because on the one hand,it is essential for the production of vitamin D,but on the other hand,it can be very harmful to the skin(increased risk for skin carcinogenesis and accelerated photoaging).Exposure to ultraviolet B radiation is a significant determinant of vitamin D status.During exposure to sunlight,the solar UVB photons(290-315 nm)are absorbed by 7-dehydrocholesterol in the skin and converted to previtamin D(3),which then undergoes a rapid transformation within the plasma membrane to vitamin D(3).During the winter at latitudes above circa 35 degrees,there is a minimal previtamin D(3)production in the skin[1].Because of that,the prophylactic intake of vitamin D as a pharmacological preparation during the winter at latitudes above 35 degrees is beneficial.Vitamin D status is not only determined by exposure to UVB and limited sources in food,but small effects of polymorphisms in the genes for key proteins involved in vitamin D production and metabolism are also present.The half-life of 25(OH)D is affected by calcium intake.Fat tissue has a function as a reservoir for the parent vitamin D,which is released during the reductions in adiposity.Skeletal muscle might also be an important site of 25(OH)D sequestration,protecting this metabolite from degradation by the liver,because of what exercise is usually associated with better vitamin D status[2].

关 键 词：VITAMIN WINTER RESERVOIR 

分 类 号：F42[经济管理—产业经济]