单纯男方HIV阳性夫妇的自然备孕与辅助生殖技术助孕  

Natural conception and conception with assisted reproductive technique for male only HIV positive couples

作　　者：房圣梓 何桂元 邵小光 Fang Shengzi;He Guiyuan;Shao Xiaoguang(Dalian Municipal Women and Children's Medical Center(Group),Center for Reproductive and Genetic Medicine,Dalian 116037,China)

机构地区：[1]大连市妇女儿童医疗中心(集团)生殖与遗传医学中心,大连116037

出　　处：《中华生殖与避孕杂志》2022年第7期751-756,共6页Chinese Journal of Reproduction and Contraception

摘　　要：随着长期有效的抗逆转录病毒治疗(highly active antiretroviral therapy,HAART)不但显著地改善了人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染男性的生存预期,而且明显降低了性接触传染的风险性。暴露前预防(pre-exposure prophylaxis,PrEP)和易孕期定时精准合房,明显提高了HIV非感染女性伴侣对性传播感染的预防效果,已经证明是单纯男方HIV阳性夫妇自然受孕的有效方式。利用HIV感染男性的处理后的精子进行辅助生殖助孕,目前并没有发现女方或子代的感染,是单纯男方HIV阳性夫妇在生殖能力下降时的首选治疗手段。HIV感染者的生活质量与生育愿望不能被忽视。With the implement of long-term effective highly active antiretroviral therapy(HAART),it not only significantly improves the survival expectation of HIV-infected men,but also significantly reduces the risk of sexually transmitted infections.The combination of pre-exposure prophylaxis(PrEP)and precisely timed intercourse during easy pregnancy period significantly improves the prevention of HIV non-infected female partners from sexually transmitted infection,and has proved to be an effective way for male only HIV positive couples to conceive naturally.Using processed semen of HIV-infected men for assisted reproduction treatment,no female partner or children infection is found,which is the preferred treatment for male only HIV positive couples with decreased fertility.The quality of life and fertility desires of HIV infected people cannot be ignored.

关 键 词：人类免疫缺陷病毒 暴露前预防 生殖技术 辅助 自然妊娠 定时合房 性接触传染 

分 类 号：R714.8[医药卫生—妇产科学] R512.91[医药卫生—临床医学]