MALDI-TOF MS精确表征单一分子量聚己内酯研究  

Characterization of discrete polycaprolactone by MALDI-TOF mass spectrometry

作　　者：胡丽华 张正彪[2] 施秋楠 HU Li-hua;ZHANG Zheng-biao;SHI Qiu-nan(Analysis and Testing Center,Soochow University,Suzhou 215123,China;College of Chemistry,Chemical Engineering and Materials Science,Soochow University,Suzhou 215123,China)

机构地区：[1]苏州大学分析测试中心,江苏苏州215123 [2]苏州大学材料与化学化工学部,江苏苏州215123

出　　处：《化学研究与应用》2022年第8期1880-1883,共4页Chemical Research and Application

基　　金：国家自然科学基金项目(21925107)资助。

摘　　要：应用基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)法表征了单一分子量己内酯八聚体,比较了不同基质对样品的影响。结果表明,几种常见基质均可有效地使样品离子化,其中使用DCTB基质所得到的谱图具有较高的信噪比和分辨率。此外,还考察了不同金属离子与样品形成加合离子的情况,并对己内酯八聚体与金属离子加合性的关系进行了分析。Discrete polycaprolactone(oCL_(8))was successfully characterized by matrix-assisted laser desorption/ionization mass spectrometry(MALDI-TOF MS).The influence of various experimental parameters(matrices and metal ions)was studied.The results showed that the matrix DCTB proved superior with higher S/N and resolution ratio.Furthermore,different cationization agents were exploited to study the effect on oCL_(8) and the relationships between oCL_(8) and metal ions were also investigated.

关 键 词：聚己内酯 基质辅助激光解吸电离飞行时间质谱 基质 金属离子 

分 类 号：O657.6[理学—分析化学]