The genus Strobilanthes:phytochemistry and pharmacology  

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作  者:Xiao-Ling Zhu Yang Xu De-Juan Sun Hua Li Li-Xia Chen 

机构地区:[1]Wuya College of Innovation,Key Laboratory of Structure-Based Drug Design&Discovery,Ministry of Education,Shenyang Pharmaceutical University,Shenyang,110016,China [2]School of Pharmacy,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430030,China

出  处:《TMR Modern Herbal Medicine》2022年第3期22-38,共17页TMR现代中药

基  金:The authors thank the National Natural Science Foundation of China(NSFC)(No.82141216);Chunhui Program-Cooperative Research Project of the Ministry of Education,Liaoning Province Natural Science Foundation(No.2020-MZLH-31);China Postdoctoral Science Foundation(No.2021M693957);Shenyang Young and Middle-aged Innovative Talents Support Program(RC210446);Project of the Educational Department of Liaoning Province(No.LJKZ0919)for financial supports.

摘  要:The genus Strobilanthes belonging to the family Acanthaceae,is mainly distributed in Kashmir,Bhutan,Bangladesh and the Khasi mountains of northeast India and southwest of China.The main purpose of this review is to provide the available information on the phytochemistry,pharmacology and the traditional applications aspects of the genus Strobilanthes,and provides trends and perspectives for the further studies on its chemical constituents.The present review collected the literatures published prior to 2022 on the phytochemistry,and pharmacology of the genus Strobilanthes.The available literatures were excerpted from scientific databases,such as Sci-finder,PubMed,Web of Science,Google Scholar,and CNKI,Baidu Scholar,books,and others.The plants from the genus Strobilanthes have been usually used in some traditional herbal prescriptions,and pharmacological researches in vitro and in vivo revealed that the extracts possessed significant anticancer,antioxidant,anti-inflammatory,anti-allergic activities,etc.To date,the majority of articles mainly focused on the research of crude extracts.However,the data in previous literatures indicated the research potential of this genus in phytochemical and pharmacological aspects.In addition,the further in-depth investigations on the safety,efficacy,as well as the specific chemical composition,stereo-chemistry and structure-activity relationships of pure compounds from this genus are essential in the future investigation.

关 键 词:Genus Strobilanthes ACANTHACEAE PHYTOCHEMISTRY PHARMACOLOGY 

分 类 号:R284[医药卫生—中药学] R285[医药卫生—中医学]

 

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