早产儿脑损伤的MRI扩散张量成像及超声诊断分析  

MRI Diffusion Tensor Imaging and Ultrasound Diagnosis of Brain Damage in Premature Infants

作　　者：洪菲[1] 叶蕾[1] 宋磊[1] HONG Fei;YE Lei;SONG Lei(The First People's Hospital of Nantong City,Nantong 226000,Jiangsu province,China)

机构地区：[1]江苏省南通市第一人民医院,江苏南通226000

出　　处：《中国CT和MRI杂志》2022年第9期6-8,共3页Chinese Journal of CT and MRI

基　　金：江苏省南通市级课题(MA201900)。

摘　　要：目的 探讨早产儿脑损伤的核磁共振成像(MRI)扩散张量成像(DTI)超声诊断价值。方法 回顾性选取本院2018年6月至2020年2月期间收治的68例缺氧缺血性脑损伤(HIBD)早产儿作为研究对象,根据病情严重程度将68例早产儿HIBD分为轻度组(n=29例)、中度组(n=23例)、重度组(n=16例),统计分析DTI和超声对HIBD的诊断价值。结果 DTI诊断HIBD准确率为94.12%(64/68)高于超声的50%(34/68)(P<0.05);DTI诊断HIBD轻度、中度、重度的灵敏度、特异度、准确度均高于超声(P<0.05);重度组额叶白质、半卵圆中心、内囊前肢、内囊后肢、胼胝体膝部、胼胝体压部和豆状核FA值低于中度组和轻度组(F=9.273;F=17.006;F=9.529;F=60.075;F=2 0.256;F=13.473;F=20.256;P<0.05)。结论 DTI对早产儿HIBD的诊断价值高于超声,能为病情评估提供客观依据。Objective To explore the diagnostic value of magnetic resonance imaging(MRI) diffusion tensor imaging(DTI) and ultrasound in brain damage of prematu re infants.Methods A total of 68 premature infa nts with hypoxic-ischemic brain damage(HIBD) admitted to the hospital from June 2018 to February 2020 were retrospectively selected as study subjects.According to disease severity,they were divided into mild group(n=29),moderate group(n=23) and severe group(n=16),and the diagnosis value of HIBD by DTI and ultrasound was statistically analyzed.Results The diagnostic accu racy rate of DTI for HIBD was higher than that of ultrasound [94.12%(64/68) vs 50%(34/68)](P<0.05).The diagnostic sensitivity,specificity a nd accuracy of DTI fo r mild,moderate and severe HIBD were higher than those of ultrasound(P<0.05).The FA values of fro ntal white matte r,semi-oval center,anterior limb of internal ca psule,posterior limb of internal capsule,corpus callosum genu,tubera corporis callosi and lentiform nucleus were lower in the severe group than in the moderate and mild groups(F=9.273;F=17.006;F=9.529;F=60.075;F=20.256;F=13.473;F=20.256;P<0.05).Condusion The diagnostic value of DTI for HIBD in prete rm infants is higher than that of ultrasound,which can provide o bjective basis for disease evaluation.

关 键 词：缺氧缺血性脑损伤 核磁共振成像 扩散张量成像 早产儿 超声 

分 类 号：R445.2[医药卫生—影像医学与核医学]