肺腺癌CT影像组学特征与病理结果对照研究  

A Comparative Study of CT Radiomics Features and Pathological Results of Lung Adenocarcinoma

作　　者：王亮[1] 孔令淳 王泽学[2] WANGg Liang;KONG Ling-chun;WANG Ze-xue(Department of Radiology,Central Hospital Affiliated to Shenyang Medical College,Shenyang 110075,Liaoning Province,China;Department of Thoracic Surgery,Central Hospital Affiliated to Shenyang Medical College,Shenyang 110075,Liaoning Province,China)

机构地区：[1]沈阳医学院附属中心医院放射科,辽宁沈阳110075 [2]沈阳医学院附属中心医院胸外科,辽宁沈阳110075

出　　处：《中国CT和MRI杂志》2022年第9期109-111,共3页Chinese Journal of CT and MRI

摘　　要：目的 评估电子计算机断层扫描(CT)成像影像组学技术在鉴别肺腺癌浸润性上的预测价值。方法 回顾分析本院收治的121肺腺癌患者的CT影像资料,使用CT影像组学技术提取CT特征,并使用受试者工作特征曲线(ROC)分析相关特征参数在预测肺腺癌浸润性上的价值。结果 浸润组的病灶大小和平均CT值与微浸润组差异显著(P<0.05)。病灶大小的AUC=0.726,特异度为84.48%,敏感度为53.9 7%;平均CT值的AUC=0.781,特异度为87.93%,敏感度为61.9 0%;CT影像组学特征模型对肺腺癌浸润性的AU C=0.962,特异度为94.83%敏感度为82.54%。结论 CT影像组学可以鉴别肺腺癌的浸润情况,特异度和敏感度较高。Objective To evaluate the value of computerized tomography(CT) radiomics technique in invasion identification of lung adenocarcinoma.Methods This study retrospectively analyze the CT imaging data of 121 patients with lung adenocarcinoma admitted to the hospital.CT features were collected using CT radiomics technique,and the value of relevant parameters in predicting invasion of lung adenocarcinoma was analyzed using the receiver operating characteristic(ROC) curve.Results The lesion size and mean CT value of the invasion group were significantly different from those of the micro-invasion group(P<0.05).The area under the curve(AUC),specificity and sensitivity of lesion size were 0.726,84.48% and 53.97%,which of mean CT value were 0.781,87.93% and 61.90%.The AUC,specificity and sensitivity of the prediction model constructed based on CT radiomics features for invasion of lung adenoca rcinoma were 0.962,94.83% and 82.54%,respectively.Conclusion CT radiomics technique ca n be used to identify invasion of lu ng adenoca rcinoma,with high specificity and sensitivity.

关 键 词：肺腺癌 电子计算机断层扫描成像 影像组学 

分 类 号：R445.3[医药卫生—影像医学与核医学]