腹腔镜辅助下急性胃十二指肠穿孔修补术对患者胃肠道功能恢复的影响  

Effect of laparoscopic assisted repair of acute gastroduodenal perforation on the recovery of gastrointestinal function

作　　者：徐焕成 杨伟高 张同领 XU Huancheng;YANG Weigao;ZHANG Tongling(Department of General Surgery,Xinyi People's Hospital,Xinyi,Jiangsu,221400,China)

机构地区：[1]新沂市人民医院普外科,江苏新沂221400

出　　处：《当代医学》2022年第20期25-27,共3页Contemporary Medicine

摘　　要：目的 探讨腹腔镜辅助下急性胃十二指肠穿孔修补术对患者胃肠道功能恢复的影响。方法 选取2018年1月至2021年1月本院收治的60例急性胃十二指肠穿孔患者作为研究对象,根据治疗方案不同分为两组,每组30例。比对组采用开腹修补术,实验组采用腹腔镜辅助下急性胃十二指肠穿孔修补术,比较两组胃肠道功能、生命质量及不良反应发生情况。结果 实验组胃蛋白酶原Ⅰ、胃蛋白酶原Ⅱ、胃泌素、血管活性肠多肽与胃动素水平分别为(107.08±9.65)μg/L、(21.18±1.78)μg/L、(23.21±2.40)ng/L、(175.15±4.52)ng/L、(144.05±9.65)ng/L,均高于比对组的(92.11±5.21)μg/L、(18.12±1.21)μg/L、(20.53±2.35)ng/L、(145.02±3.25)ng/L、(119.65±6.52)ng/L,差异有统计学意义(P<0.05)。实验组心理状态、社会功能、生理功能及情感职能评分分别为(91.95±4.60)、(91.96±4.65)、(92.31±4.66)、(92.25±4.68)分,均高于比对组的(80.65±4.12)、(81.12±4.20)、(81.25±4.25)、(81.29±4.29)分,差异均有统计学意义(P<0.05)。实验组不良反应发生率为10.00%,低于比对组的33.33%,差异有统计学意义(P<0.05)。结论 急性胃十二指肠穿孔发病率较高,应用腹腔镜辅助下急性胃十二指肠穿孔修补术治疗安全性高,可提高患者胃肠道功能与生命质量,临床应用价值较高。Objective To explore the effect of laparoscopic assisted repair of acute gastroduodenal perforation on the recovery of gastrointestinal function. Methods A total of 60 patients with acute gastroduodenal perforation admitted to our hospital from January 2018 to January 2021 were selected as the research subjects, and they were divided into two groups according to different treatment plans, with 30 cases in each group. The control group was treated with open repair, and the experimental group was treated with repair of acute gastroduodenal perforation. The gastrointestinal function, quality of life and adverse reactions were compared between the two groups. Results The levels of pepsinogen Ⅰ, pepsinogen Ⅱ, gastrin, vasoactive intestinal polypeptide and motilin in the experimental group were(107.08±9.65) μg/L,(21.18±1.78) μg/L,(23.21±2.40) ng/L,(175.15±4.52)ng/L,(144.05±9.65) ng/L respectively, higher than(92.11±5.21) μg/L,(18.12±1.21) μg/L,(20.53±2.35)ng/L,(145.02±3.25)ng/L,(119.65±6.52) ng/L in the control group, the difference was statistically significant(P<0.05). The scores of psychological state, social function, physiological function and emotional function in the experimental group were(91.95±4.60),(91.96±4.65),(92.31±4.66),(92.25±4.68) scores respectively, which were significantly higher than(80.65±4.12),(81.12±4.20),(81.25±4.25),(81.29±4.29) scores in the control group, the difference was statistically significant(P<0.05). The incidence of adverse reactions in the experimental group was 10.00%, which was lower than 33.33% in the control group, the difference was statistically significant(P<0.05). Conclusion The incidence rate of acute gastroduodenal perforation is high, the application of laparoscopy assisted gastroduodenal perforation repair is safe and can improve the gastrointestinal function and daily life quality of patients.

关 键 词：急性胃十二指肠穿孔修补术 胃肠道功能 腹腔镜 

分 类 号：R656.6[医药卫生—外科学]