机构地区:[1]复旦大学附属儿科医院新生儿科,上海市201102 [2]复旦大学附属儿科医院医学统计部,上海市201102 [3]复旦大学附属儿科医院上海市出生缺陷重点实验室,上海市201102 [4]复旦大学附属儿科医院护理部,上海市201102 [5]宁波市妇幼保健院护理部 [6]安徽省儿童医院新生儿科 [7]无锡市儿童医院新生儿科 [8]苏州市立医院新生儿科
出 处:《中华护理杂志》2022年第16期1956-1961,共6页Chinese Journal of Nursing
基 金:上海市科委长三角联合攻关项目(18495810800);复旦大学校级课题(FNF202145);国家儿童医学中心儿科临床研究院课题(2020ZBDL23)。
摘 要:目的分析长三角地区各医疗机构的极/超低出生体重儿不同乳品种类搭配喂养的现状,为临床中该类群体喂养方式的选择提供依据。方法2019年1月—12月,采用NICU极/超低出生体重儿喂养情况调查表,回顾性收集长三角地区5所三级甲等医院NICU胎龄≤35周且出生后24 h内入院的极/超低出生体重儿的临床资料,获得不同乳品种类搭配喂养的情况,同时比较纯母乳喂养组和亲母母乳不足时使用配方奶补足组患儿喂养的相关临床指标。结果共收治极/超低出生体重儿830例,最终纳入667例。其中仅接受亲母母乳喂养82例(12.3%),仅接受捐赠母乳喂养5例(0.8%),接受亲母母乳+捐赠母乳喂养65例(9.8%),以上3种方式统称为纯母乳喂养,共计152例(22.9%)。接受捐赠母乳+配方奶喂养34例(5.1%),仅接受配方奶喂养75例(11.2%),接受亲母母乳+配方奶喂养333例(49.9%),接受亲母母乳+捐赠母乳+配方奶喂养73例(10.9%)。使用纯母乳喂养组肠外营养天数少于配方奶补足组,坏死性小肠结肠炎和迟发性败血症的发生率更低,差异均具有统计学意义(P<0.05)。结论长三角地区各医疗机构的极/超低出生体重儿纯母乳喂养情况不容乐观,亲母母乳不足时以配方奶进行补足喂养仍然不如纯母乳喂养效果好。Objective To analyze the application status of different dairy products for very and extremely low birth weight infants in Yangtze River Delta,so as to provide evidence for making better feeding choices in clinic Practice.Methods From January 2019 to December 2019,the self-made“form of feeding situation in very low birth weight infants(VLBW)in neonatal intensive care unit(NICU)”was used to collect data and uploaded to the database,and the clinical data of VLBW infants with gestational age≤35 weeks and admitted to the NICU within 24 hours after birth in 5 tertiary hospitals in the Yangtze River Delta were retrospectively analyzed,and the composition ratio of different dairy types was obtained.At the same time,the clinical outcomes related to feeding in the exclusive breastfeeding group and the formula supplement group were compared.Results 830 cases of VLBW infants were admitted to the NICUs of 5 hospitals,among which 667 cases met the inclusion criteria.Among them,82(12.3%)received exclusive maternal breast milk;5(0.8%)received exclusive donated breast milk;65(9.8%)received both maternal and donated breast milk,the above three feeding types were collectively referred to as exclusive breastfeeding,a total of 152(22.9%)cases.34(5.1%)received both donated breast milk and formula;75(11.2%)received exclusive formula;333(49.9%)received both maternal breast milk and formula;73(10.9%)received formula,maternal and donated breast milk.The number of days of parenteral nutrition in the donor breast milk supplement group was less than that in the formula supplement group,and the incidence of necrotizing enterocolitis and septicemia was lower than that in the formula supplement group,with statistical significance(P<0.05).Conclusion The exclusive breastfeeding rate of VLBW infants in various institutions in the Yangtze River Delta region is not optimistic.When the mother’s breast milk is insufficient,formula supplement feeding is still not as effective as exclusive breastfeeding.
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