新型冠状病毒检测技术研究进展  

Advances in SARS-CoV-2 diagnostic strategies during the later COVID-19 era

作　　者：龙秋月 郑雅莉 高占成[2] Long Qiuyue;Zheng Yali;Gao Zhancheng(Department of Respiratory,Critical Care and Sleep Medicine,Xiang′an Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen 361102,China;Department of Respiratory and Critical Care Medicine,Peking University People′s Hospital,Beijing 100044,China)

机构地区：[1]厦门大学附属翔安医院呼吸与危重症和睡眠医学科,厦门361102 [2]北京大学人民医院呼吸与危重症医学科,北京100044

出　　处：《中华结核和呼吸杂志》2022年第8期819-825,共7页Chinese Journal of Tuberculosis and Respiratory Diseases

基　　金：国家自然科学基金青年科学基金项目(8200011769)。

摘　　要：尽管自然感染或疫苗接种已经初步建立了群体保护屏障,但随着多种新冠病毒变异体的持续出现,突破性感染仍然无法完全避免,新冠病毒检测仍是发现传染源和中断传播链的关键。目前,以核酸、抗原、抗体检测为基础的新冠病毒检测形式呈多元化发展。在相对疫情早期的后新冠时代,复工复产和疫情防控常态化,需要我们根据不同场景的防控需求选择合适的检测手段。本文总结了现有新冠病毒检测技术的原理及其适用特征,以期为临床及公共卫生人员提供精准化决策依据。Based on natural infection or vaccination,the protective barrier for population has been preliminarily established.However,with constant appearances of SARS-CoV-2 variants,breakthrough infection events cannot be completely avoided,and thus the diagnostic strategy is still the key to discovering epidemic sources and blocking the transmission chain.Currently,SARS-CoV-2 diagnosis technologies based on nucleic acid,antigen and antibody detections have developed and extended in diversity.Under the background of work resumption and epidemic-prevention normalization during the later COVID-19 era,it is necessary for us to choose appropriate detection methods to satisfy the need of epidemic prevention and control in various scenarios.We summarized the principles and applicable characteristics of existing SARS-CoV-2 detection technologies in this paper,aimed to provide guidance for clinical and public health personnel to make targeted decisions.

关 键 词：疫苗接种 病毒检测技术 保护屏障 病毒变异 抗体检测 疫情防控 自然感染 传播链 

分 类 号：R446.5[医药卫生—诊断学]