富血小板血浆改善肠道吻合口愈合的研究进展  

A review of platelet-rich plasma in improving intestinal anastomotic healing

作　　者：单悦展 阿古 高佳旭 周远航 赵婷婷[3] 杨佶军 于晟曼 陶有茂[1] Shan Yuezhan;A Gu;Gao Jiaxu;Zhou Yuanhang;Zhao Tingting;Yang Jijun;Yu Shengman;Tao Youmao(Department of Gastrointestinal Surgery,Colorectal and Anal Surgery,China-Japan Union Hospital of Jilin University,Changchun 130033,China;Department of Forensic Medicine,Jilin Shiran Forensic Expertise Center,Changchun 130028,China;Operating Room,Xinmin District,China-Japan Union Hospital of Jilin University,Jilin University,Changchun 130033,China;Department of Blood Transfusion,China-Japan Union Hospital of Jilin University,Changchun 130033,China;College of Medical Technology,Beihua University,Wuhan 430212,China)

机构地区：[1]吉林大学中日联谊医院胃肠外科,长春130033 [2]吉林释然司法鉴定中心,长春130028 [3]吉林大学中日联谊医院新民院区手术室,长春130033 [4]吉林大学中日联谊医院输血科,长春130033 [5]北华大学医学技术学院,吉林132013

出　　处：《中华实验外科杂志》2022年第7期1423-1425,共3页Chinese Journal of Experimental Surgery

摘　　要：肠道吻合口愈合是消化道手术术后面临的重要问题,处理不当易造成吻合口漏,进而诱发脓毒血症及感染性休克,甚至危及生命。富血小板血浆(PRP)由自体全血浓缩得到,其血小板浓度高于全血基线水平且包含多种生长因子,可使复杂性创口快速愈合,减少患者住院时间,因而被广泛应用在皮肤、肩关节等领域。近年来,PRP在消化道手术中的应用受到广泛关注。然而,目前关于PRP改善吻合口愈合的研究多集中于动物实验,缺乏统一标准,效果不完全统一,尚未应用于临床。本文以PRP改善肠道吻合口愈合为切入点,系统阐述PRP改善肠道吻合口愈合的研究进展,为其临床应用提供参考。Anastomotic healing is an important problem after gastrointestinal surgery.Improper handling can easily lead to anastomotic leakage,further inducing sepsis,septic shock,and even life-threatening.Platelet-rich plasma(PRP)is an autologous blood product composed of concentrated platelets.Its platelet concentration is higher than the baseline level of the whole blood.It contains a variety of growth factors,making it practical for quickly healing complex wounds and reducing the length of hospital stay.Therefore,it is widely used in skin and shoulder joints.In recent years,the application of PRP in gastrointestinal surgery has received extensive attention.However,the current research on improving anastomotic healing by PRP mainly focuses on animal experiments,lacks uniform standards,and the effects are not entirely accordant,which has strained its clinical application.This article takes the improvement of intestinal anastomotic healing by PRP as a point of entry,systematically expounds on the research progress of PRP in improving intestinal anastomotic recovery to provide a reference for promoting its clinical application.

关 键 词：富血小板血浆 吻合口漏 愈合 

分 类 号：R656[医药卫生—外科学]