经典名方大建中汤的文献考究  

Textual research on classical famous prescription Dajianzhong Decoction

作　　者：刘洺希 张宁 高崎 胥孜杭 王冰 朱国琴 邹纯朴[1] LIU Ming-xi;ZHANG Ning;GAO Qi;XU Zi-hang;WANG Bing;ZHU Guo-qin;ZOU Chun-pu(School of Basic Medicol Science,plication and Research Cenler of Cassical Preseripion,Seience and Tecnology Experiment Center,Shanghai University of Traditionl Chinese Medicine,Shanghai 201203,China;Shenghai Xingling Technology Pharmaceuical Co.,Ltd.,Shanghai 201203,China;Pharmaceutieal Preparation Research Cenuer,Shanghai Institute of Mueria Medicu,Chinese Acudemy of Sciences,Shonghai 201203,China)

机构地区：[1]上海中医药大学基础医学院经方理论应用研究中心科技实验中心,上海201203 [2]上海上药杏灵科技药业股份有限公司,上海201203 [3]中国科学院上海药物研究所药物制剂研究中心,上海201203

出　　处：《中国中药杂志》2022年第15期4025-4032,共8页China Journal of Chinese Materia Medica

基　　金：上海市2020年度“科技创新行动计划”生物医药科技支撑专项(20S21902400);上海市进一步加快中医药事业三年行动计划(2018—2020)项目[ZY(2018—2020)-CCCX-2001-01]。

摘　　要：经典名方大建中汤出自东汉张仲景的《金匮要略》,其历史悠久,临床效果确切,但是目前尚未转化成为中成药制剂。采用文献计量学方法,搜集大量古代医籍,共得到有效数据211条,涉及相关中医古籍67部。从大建中汤的历史发展源流、主治病证、制方原理、药物基原、炮制方法和煎煮方法等进行统计、分析。摘取了各代医家对该方药物组成、条文理解的不同观点;其剂量虽有不同,但干姜与人参比例相对恒定。探讨了其他大建中汤方的源流,希望为大建中汤的复方制剂研发提供思路,也为其他经方的传承和创新提供参考借鉴。The classical famous prescription Dajianzhong Decoction is recorded in Synopsis of the Golden Chamber written by Zhang Zhongjing in the Eastern Han Dynasty. It has a long history and definite clinical effects, while this prescription has not been manufactured into Chinese patent medicine preparation. We collected many ancient books of traditional Chinese medicine(TCM) by using the method of bibliometrics and got 211 valid data terms which involved 67 ancient books. The history, main treated syndromes, formulation principle, origins and processiong of medicinal materials, and decoction method of Dajianzhong Decoction were analyzed. Despite the different views of various generations of medical experts toward the composition of this prescription, the compatibility ratio of Ginseng Radix et Rhizoma to Zingiberis Rhizoma Recens is constant. Furthermore, we explored the origins of synonyms of Dajianzhong Decoction. On the basis of this study, we hope to gain an insight into the research and development of the compound preparations of Dajianzhong Decoction and provide reference for the heritage and innovation of other classical prescriptions.

关 键 词：经典名方 大建中汤 文献考证 药物炮制 《金匮要略》 

分 类 号：R289.5[医药卫生—方剂学]