胰源性门静脉高压症治疗进展  

Progress in the treatment of pancreatic sinistral portal hypertension

作　　者：任加强 武帅[1] 韩亮[1] 仵正[1] REN Jiaqiang;WU Shuai;HAN Liang;WU Zheng(Department of Hepatobiliary Surgery,First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,P.R.China)

机构地区：[1]西安交通大学第一附属医院肝胆外科,西安710061

出　　处：《中国普外基础与临床杂志》2022年第8期992-996,共5页Chinese Journal of Bases and Clinics In General Surgery

基　　金：陕西省科技创新能力支撑项目(项目编号:2022PT-35)。

摘　　要：胰源性门静脉高压症(pancreatic sinistral portal hypertension,PSPH)是由胰腺疾病导致脾静脉回流受阻而引起的一种临床综合征,其病因主要包含急、慢性胰腺炎,胰腺肿瘤以及胰腺手术相关的医源性因素。PSPH患者大多表现为孤立性胃静脉曲张、脾肿大和脾功能亢进,肝功能多正常,胃底曲张静脉破裂所致上消化道出血为其最严重的临床表现。PSPH的治疗可分为脾胃区门静脉高压症的治疗,包括密切随访、药物治疗、内镜治疗、脾动脉栓塞术、脾切除术等;对胰腺原发疾病的治疗主要针对急性、慢性胰腺炎以及胰腺肿瘤;特别是与胰腺手术术式相关的PSPH值得关注。Pancreatic sinistral portal hypertension(PSPH)is a clinical syndrome resulting from pancreatic disease that blocks splenic vein return,which includes acute and chronic pancreatitis,pancreatic tumors,and iatrogenic factors related to pancreatic surgery.Most PSPH patients present with isolated gastric varices,splenomegaly and hypersplenism,with normal liver function,and upper gastrointestinal bleeding caused by varices in the fundus of the stomach is the most serious clinical manifestation.The treatment of PSPH can be divided into the treatment of portal hypertension in the spleen and stomach region,including close follow-up,medication,endoscopic therapy,splenic artery embolization and splenectomy,etc.The primary diseases of pancreas are mainly treated for acute pancreatitis,chronic pancreatitis and pancreatic tumor.In particular,PSPH related to pancreatic surgery should be concerned.

关 键 词：胰源性门静脉高压症 胃静脉曲张 脾切除术 胰腺原发疾病 胰腺手术 

分 类 号：R657.5[医药卫生—外科学]