Innovative Light Therapy:5.Anti-stress Effects of Polarized Polychromatic and Monochromatic Light from Halogen and LED Sources  

作　　者：Sergiy A.Gulyar Zynaida A.Tamarova Victor V.Taranov 

机构地区：[1]Department of Sensory Signaling,Bogomoletz Institute of Physiology National Academy of Sciences of Ukraine,Kyiv 401601,Ukraine [2]International Medical Innovation Center Zepter,Kyiv 02152,Ukraine [3]National Technical University of Ukraine“Igor Sikorsky Kyiv Polytechnic Institute”,Kyiv 03056,Ukraine

出　　处：《Journal of US-China Medical Science》2022年第2期29-45,共17页美中医学（英文版）

基　　金：This study became possible due to support of Philip Zepter,President of the Zepter International,and Diana Zepter,Chief Executive Officer of the Zepter International.

摘　　要：In experiments on laboratory animals(n=100)and in examinations of people(n=42),the anti-stress effect of low-intensity polychromatic or monochromatic halogen light of the Bioptron device(PILER/PL:480-3,400 nm,40 mW/cm2)and LED(light-emitting diode)light of the Medolight-polychrome device(401+467.5+527.5+640.5+940 nm)has been demonstrated objectively.We found out that adult rodents(white mice)showed that 30 min of immobilization stress increased grooming duration by 330%,and after a PL(polarized light)session to acupuncture point(AP)E-36-only by 170%-230%compared to the norm.PL’s anti-stress effect was determined by its wavelength.Researchers found that red light(the long-wavelength part of the visible light spectrum)had a significantly greater anti-stress effect than green light(medium-wavelength).Red PL application reduced stress-induced grooming by 49.2%and other behavioural responses(sleeping,eating,and physical activity)were partially normalized,while green PL reduced grooming by 31%without affecting other behavioural responses.The short-term immobilization stress weakened the somatic pain response(formalin test)by 28.5%and the visceral one(acetate test)by 26.3%.Red PL has a less pronounced analgesic effect on animals under stress than on animals not under stress.In normal conditions,red PL suppressed somatic pain by 54.4%,visceral pain by 64%,and under stress by 31%and 46.1%,respectively.Under the action of low-intensity LED-light on AP,we have obtained experimental evidence of stress reduction in humans.The latent period for falling asleep in the subjects increased from 393.6±47.1 to 749.3±44.4 s under stress.Applying the Medolight-polychrome device to auricular AP weakened post-stress sleep disturbances:the duration of falling asleep was reduced to 512.5±38.6 s.In persons with daytime stress,the frequency of dreams was 49%±5.7%,and after a PL session it was 14.79%±5.2%.The results of these studies can be used to develop recommendations for reducing stress in humans.

关 键 词：PILER-light polarized light Bioptron LED-light monochromatic light polychromatic light GROOMING immobilization stress ANALGESIA formalin test acetate test acupuncture points sleep stress auriculotherapy 

分 类 号：R24[医药卫生—中医临床基础]