内脏脂肪与2型糖尿病血管并发症的关系研究进展  

Research progress on the relationship between visceral fat and vascular complications of type 2 diabetes mellitus

作　　者：李航天 王倩[2] 董哲毅[2] 张伟光[2] 林雯文 骆雅咏 陈香美 Li Hang-Tian;Wang Qian;Dong Zhe-Yi;Zhang Wei-Guang;Lin Wen-Wen;Luo Ya-Yong;Chen Xiang-Mei(School of Clinical Medicine,Guangdong Pharmaceutical University,Guangzhou,Guangdong 510006,China;Department of Nephrology,the First Medical Center of Chinese PLA General Hospital/Chinese PLA Institute for Nephrology/State Key Laboratory of Kidney Disease/National Clinical Research Center for Chronic Kidney Disease/Beijing Key Laboratory of Kidney Disease Research,Beijing 100853,China)

机构地区：[1]广东药科大学临床医学院,广东广州510006 [2]解放军总医院第一医学中心肾脏病医学部/解放军肾脏病研究所/肾脏疾病国家重点实验室/国家慢性肾脏病临床医学研究中心/肾脏疾病研究北京市重点实验室,北京100853

出　　处：《解放军医学杂志》2022年第8期824-830,共7页Medical Journal of Chinese People's Liberation Army

基　　金：国家重点研发计划(2018YFC1704203);北京市科技计划课题(D17110700280000、D171100002817002、D181100000118002、D181100000118004)。

摘　　要：2型糖尿病(T2DM)血管并发症包括大血管并发症和微血管并发症,其发病率的升高往往伴随着高肥胖发生率。肥胖是T2DM的独立危险因素。研究显示,体脂分布而不是体脂总量与肥胖患者的代谢及心血管风险相关。体重指数(BMI)和腰围(WC)不能准确地反映肥胖患者的体脂分布情况,因此,内脏脂肪越来越受重视,并可能成为T2DM血管并发症的预测指标。本文就内脏脂肪与T2DM血管并发症的相关性及其作用机制研究进展进行综述,以期为内脏脂肪的深入研究和临床检查提供参考。Vascular complications of type 2 diabetes mellitus(T2DM)include macrovascular complications and microvascular complications,of which the increased incidence is often accompanied with a high incidence of obesity.Obesity is an independent risk factor for T2DM.In obese patients,body fat distribution rather than total body fat is associated with metabolic and cardiovascular risk.Body mass index(BMI)and waist circumference(WC)cannot accurately reflect body fat distribution in obese patients,so visceral fat has received more and more attention and may be as a related risk factor for vascular complications in T2DM.The research progress on the relationship between visceral fat and vascular complications of T2DM and its action mechanism have been reviewed in present paper,in order to provide a reference for in-depth research and clinical examination of visceral fat.

关 键 词：肥胖 内脏脂肪 糖尿病 2型 血管并发症 

分 类 号：R589.2[医药卫生—内分泌]