分消走泄法治疗湿热型中青年高血压病的临床观察  

Clinical Observation on Method of“Elimination of Pathogens through Purgation and Diuresis”in the Treatment of Young and Middle-Aged Hypertension of Dampness-heat Type

作　　者：杨学伶 简文佳[1] 窦金娟[1] 杨贺[1] 张龙生[1] YANG Xueling;JIAN Wenjia;DOU Jingjuan;YANG He;ZHANG Longsheng(Area Five of Department of Encephalopathy,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 101100,China)

机构地区：[1]北京中医药大学东直门医院脑病科五区,北京101100

出　　处：《中国中医药现代远程教育》2022年第16期99-101,共3页Chinese Medicine Modern Distance Education of China

基　　金：北京中医药大学面上项目【No.2016-JYB-JSMS-04】。

摘　　要：目的研究“分消走泄”法代表方剂“温胆汤”治疗湿热型中青年高血压病的临床效果。方法选取2017年9月—2019年2月在北京中医药大学东直门医院患者60例,随机分成治疗组和对照组,各30例。对照组给予苯磺酸氨氯地平片(络活喜)治疗,治疗组在对照组的基础上给予“温胆汤”加减(颗粒剂),2组均以2周为1个疗程,服药2个疗程。通过观察2组患者的血压数值及中医证候的改善情况来评价患者的临床治疗效果。结果2组降压效果比较,治疗组总有效率为86.7%(26/30),对照组总有效率为83.3%(25/30),2组总有效率比较差异无统计学意义(P>0.05);中医证候疗效比较:治疗组总有效率为93.3%(28/30),对照组总有效率为63.3%(19/30),2组总有效率比较差异有统计学意义(P<0.05)。结论治疗组与对照组的降压效果无明显差异,但治疗组能明显改善患者的中医证候,说明分消走泄法是治疗湿热型中青年高血压病的有效方法,临床上值得推广,为治疗湿热型中青年高血压病提供了一种新的方法和思路。Objective To study the clinical effect of Wendan decoction that is representative prescription of“elimination of pathogens through purgation and diuresis”in treating young and middle-aged hypertension of dampness-heat type.Methods 60 cases of patients admitted to Dongzhimen Hospital of Beijing University of Chinese Medicine from September 2017 to February 2019 were randomly divided into treatment group and control group,with 30 patients in each group.The treatment group was treated with Wendan decoction(granules)and amlodipine besylate tablets(Norvasc),while the control group was treated with amlodipine besylate tablets(Norvasc).Both groups were designed for 2 weeks as a course of treatment,with 2 courses of medication.The clinical therapeutic effect of the patients was evaluated by observing the blood pressure values and the improvement of traditional Chinese medicine(TCM)syndromes of the two groups.Results The total effective rate of the treatment group was 86.7%(26/30),and that of the control group was 83.3%(25/30).There was no significant difference in the total effective rate between the two groups(P>0.05).Comparison of TCM syndrome and curative effect:the total effective rate of the treatment group was 93.3%(28/30),the total effective rate of the control group was 63.3%(19/30),and the difference between the two groups was statistically significant(P<0.05).Conclusion There is no significant difference in the antihypertensive effect between the treatment group and the control group,but the treatment group can significantly improve the TCM syndrome of the patients,which indicates that the method of“elimination of pathogens through purgation and diuresis”is an effective method for the treatment of dampness-heat young and middle-aged hypertension,and Wendan decoction can be used in the treatment of dampness-heat young and middle-aged hypertension,which provides a new method and idea for the treatment of dampness-heat young and middle-aged hypertension.

关 键 词：高血压病 中青年 湿热型 分消走泄法 温胆汤 

分 类 号：R259[医药卫生—中西医结合]