三才封髓丹加减治疗气阴两虚型2型糖尿病合并汗证疗效研究  

Clinical study on Sancai Fengsui Dan on type 2 diabetes complicated with sweat syndrome with Qiyin Liangxu

作　　者：杨川洲 彭艳文 李卫东[1] 王萌 YANG Chuanzhou;PENG Yanwen;LI Weidong;WANG Meng(Guang’anmen Hospital,Chinese Academy of Traditional Chinese Medicine,Beijing 100053,China)

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]School of Public Health and Health Professions,United States of America New York 14214

出　　处：《陕西中医》2022年第9期1204-1207,共4页Shaanxi Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金青年科学基金资助项目(81673906)。

摘　　要：目的:观察三才封髓丹加减治疗气阴两虚型2型糖尿病合并汗证的疗效。方法:采用回顾性研究方法,将68例2型糖尿病合并汗证患者分为对照组和观察组,每组34例。对照组患者在常规治疗基础上予甲钴胺片口服,观察组患者在对照组基础上加用三才封髓丹加减,两组均治疗8周。比较两组治疗前后中医证候评分、空腹血糖、餐后2 h血糖、糖化血红蛋白水平。比较两组疗效、不良反应发生情况。结果:观察组总有效率为88.2%,高于对照组的47.1%,差异有统计学意义(P<0.05)。治疗后,观察组自汗、盗汗主症评分及气短乏力、口干多饮次症评分均优于治疗前,且明显优于对照组,差异有统计学意义(均P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:常规治疗联合三才封髓丹内服治疗气阴两虚型2型糖尿病合并汗证患者,可改善糖代谢指标,临床疗效较好。Objective:To observe clinical effect of Sancai Fengsiu dan on type 2 diabetes complicated with sweat syndrome with Qiyin Liangxu.Methods:By retrospective study,68 patients with type 2 diabetes complicated with sweat syndrome with Qiyin Liangxu were divided into control group and observation group,34 cases in each group.The control group were given mecobalamin tablets orally on the basis of routine treatment,and the observation group were given Sancai Fengsui Dan on the basis of the control group.Both groups were treated for 8 weeks.TCM syndrome score,fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin levels were compared between the two groups before and after treatment.The efficacy and adverse reactions of the two groups were compared.Results:The total effective rate in the observation group was 88.2%higher than 47.1%in the control group,difference statistically significant(P<0.05).After treatment,the main scores of spontaneous sweating,night sweating,shortness of breath and fatigue,dry mouth and polydipsia in the observation group were better than those before treatment,and better than those in the control group,difference statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Conventional treatment and Sancai Fengsui Dan treated patients with type 2 diabetes complicated with sweat syndrome with Qiyin Liangxu combined with abnormal sweating,can improve glucose metabolism index and better clinical effect.

关 键 词：2型糖尿病 汗证 气阴两虚证 三才封髓丹 甲钴胺 

分 类 号：R587.1[医药卫生—内分泌]