婴儿百日咳的流行病学意义及其临床特点  

Clinical features and epidemiological significance of pertussis in infants

作　　者：姚开虎 胡亚红 袁林 YAO Kai-Hu;HU Ya-Hong;YUAN Lin(National Center for Children's Health/Beijing Children's Hospital,Capital Medical University/Laboratory of Microbiology,Beijing Pediatric Research Institute/National Key Discipline of Pediatrics(Capital Medical University)/Key Laboratory of Major Diseases in Children,Ministry of Education,Beijing 100045,China)

机构地区：[1]国家儿童医学中心/首都医科大学附属北京儿童医院/北京市儿科研究所微生物研究室/儿科学国家重点学科/教育部儿科重大疾病研究重点实验室,北京100045

出　　处：《中国当代儿科杂志》2022年第9期955-959,共5页Chinese Journal of Contemporary Pediatrics

基　　金：国家自然科学基金(81973100);北京市自然科学基金-海淀原始创新联合基金项目(19L2041)。

摘　　要：婴儿百日咳是社区百日咳持续传播的明确证据。婴儿是百日咳健康威胁最严重的群体,也是百日咳社区网状传播的重要节点,预防婴儿百日咳是疫苗免疫等防控措施的核心。目前国内报道百日咳虽然以婴儿百日咳病例为主,但实际发生的婴儿百日咳病例更多,临床上还需提高警惕和加强认识,普及相关实验室检测。在重视识别婴儿百日咳的基础上,及时诊治、随访观察和规范管理百日咳患儿的密切接触者,才能减少和阻断百日咳的社区传播。Infantile pertussis is clear evidence for the persistent transmission of pertussis in communities. Infants are the most vulnerable population for pertussis infection and are also important nodes in pertussis transmission networks in communities, and therefore, the prevention of infantile pertussis is the core of prevention and control measures against pertussis including vaccine immunization. Although the cases of pertussis reported in China are mainly infants with pertussis, the actual number of infants with pertussis might be higher than the reported number. It is necessary in clinical practice to improve the awareness of this disease and promote related laboratory tests. On the basis of emphasizing the identification of pertussis in infants, timely diagnosis and treatment, follow-up visits, and standard management of the close contacts of infants with pertussis should be performed to reduce and block the community transmission of pertussis.

关 键 词：百日咳 流行病学 临床表现 婴儿 

分 类 号：R725.1[医药卫生—儿科] R181.3[医药卫生—临床医学]