经脐单孔腹腔镜下手术治疗对嵌顿性腹股沟斜疝患儿的效果及血清CRP、β-EP水平的影响  

Effects of transumbilical single-port laparoscopy on children with incarcerated oblique inguinal hernia and its influences on levels of serum CRP andβ-EP

作　　者：宋丹[1] Song Dan(The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan,China)

机构地区：[1]河南科技大学第一附属医院手术室,河南洛阳471000

出　　处：《四川生理科学杂志》2022年第8期1330-1333,共4页Sichuan Journal of Physiological Sciences

摘　　要：目的:探讨经脐单孔腹腔镜下手术治疗嵌顿性腹股沟斜疝患儿的效果及对血清C反应蛋白(C-Reactive Protein,CRP)、β-内啡肽(Endorphin,β-EP)水平的影响。方法:回顾性分析2019年1月至2021年1月本院确诊的115例嵌顿性腹股沟斜疝患儿的临床资料,根据手术方式分为观察组(n=58)和对照组(n=57),分别采用腹腔镜疝囊高位结扎术以及开放手术进行治疗。记录两组患儿手术时间、术中出血量、下床时间、住院时间与并发症发生情况;分别于手术前后采用酶联免疫吸附试验法测定患者血清CRP、白细胞介素-6(Interleukin-6,IL-6)、肿瘤坏死因子-α(Tumor Necrosis Factor-α,TNF-α)及氧化应激指标,如β-EP、生长激素(Growth Hormone,GH)、总抗氧化能力(Total antioxidant capacity,T-AOC)水平。结果:观察组手术时间、术中出血量、下床时间、住院时间均短于对照组(P<0.05);手术后,观察组患儿CRP、IL-6、TNF-α及β-EP水平均低于对照组,GH、T-AOC均高于对照组(P<0.05)。观察组并发症发生率明显低于对照组(P<0.05)。结论:经脐单孔腹腔镜下手术治疗嵌顿性腹股沟斜疝患儿的效果较好,可促进患儿早期康复,降低血清CRP、β-EP水平及并发症发生风险。Objective:To explore the effects of transumbilical single-port laparoscopy on children with incarcerated oblique inguinal hernia and its influences on levels of serum C-reactive protein(CRP)andβ-endorphin(β-EP).Methods:A total of 115 children with incarcerated oblique inguinal hernia confirmed in the hospital were enrolled for retrospective analysis between January 2019 and January 2021.According to different surgical methods,they were divided into observation group(n=58,laparoscopic high ligation of hernia sac)and control group(n=57,open surgery).The operation time,intraoperative blood loss,leaving bed time and hospitalization time in both groups were recorded.Before and after surgery,use enzyme-linked immunosorbent assay levels of serum CRP,interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and oxidative stress indexes,includingβ-EP,growth hormone(GH)and total antioxidant capacity(T-AOC).Results:The operation time,intraoperative blood loss,leaving bed time and hospitalization time in observation group were lower than those in control group(P<0.05).After surgery,levels of CRP,IL-6,TNF-αandβ-EP in observation group were lower than those in control group,while GH and T-AOC were higher than those in control group(P<0.05).The incidence of complications in observation group was lower than that in control group(P<0.05).Conclusion:Curative effect of transumbilical single-port laparoscopy is good on children with incarcerated oblique inguinal hernia,which can promote early recovery,reduce levels of serum CRP andβ-EP,and the complications risk.

关 键 词：经脐单孔腹腔镜 疝囊高位结扎术 嵌顿性腹股沟斜疝 血清C反应蛋白 β-内啡肽 

分 类 号：R656.21[医药卫生—外科学]