新发现的骆驼朊病毒病  

Introduction to the Camel Prion Disease Identified Recently

作　　者：刘雨田[1] 于小静[1] 迟田英[1] 宋芳芳 吴晓东[1] Liu Yutian;Yu Xiaojing;Chi Tianying;Song Fangfang;Wu Xiaodong(China Animal Health and Epidemiology Center,Qingdao,Shangdong 266032,China)

机构地区：[1]中国动物卫生与流行病学中心,山东青岛266032

出　　处：《中国动物检疫》2022年第9期1-4,共4页China Animal Health Inspection

摘　　要：骆驼朊病毒病是近来在北非地区发现的感染单峰驼的传染性海绵状脑病。发病骆驼年龄均在8岁以上,病程3~8个月,以行为异常、共济失调、反应过敏、不时倒地、站立困难为特征;在脑部特定区域出现海绵状空泡病变,通过免疫组化和免疫印迹方法能够检测到朊病毒。世界动物卫生组织(WOAH)暂未将该病判定为新发病。由于相关信息非常有限,本文仅对该病的起源、临床症状、病理变化、病原特点、WOAH观点、防控建议等进行简要介绍,以期引起我国动物疫病防控管理部门和相关从业人员的警惕。Camel prion disease is an infectious spongiform encephalopathy identified in single-hump camels in North Africa in recent years.All infected camels are over 8 years old,with a course of 3-8 months,and the characteristics of abnormal behaviors,ataxia,anaphylaxis,occasional falls and difficulty in standing;spongy vacuolar lesions were observed in the specific area of brain,and prion could be detected by immunohistochemistry and western blotting,which has not been classified as an emerging disease by World Organization for Animal Health(WOAH).In the paper as relevant information was very limited the origin clinical symptoms pathological changes pathogenic characteristics opinions proposed by WOAH and recommendations on prevention and control of the disease were introduced with a view to alerting the authorities for animal disease prevention and control and relevant practitioners in China to the disease.

关 键 词：朊病毒 单峰驼 临床症状 病原检测 防控建议 

分 类 号：S851.3[农业科学—预防兽医学]