Viabahn覆膜支架治疗下肢动脉硬化闭塞症的临床疗效  

Clinical efficacy of Viabahn stent graft in the treatment of lower limb arteriosclerosis obliterans

作　　者：韩兵[1] 王利[1] 薛娟 Han Bing;Wang Li;Xue Juan(Vascular Surgery Department,Tianjin Port Hospital,Tianjin 300456,China;School of Pharmacy,Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China)

机构地区：[1]天津港口医院血管外科,天津300456 [2]贵州中医药大学药学院,贵阳550025

出　　处：《保健医学研究与实践》2022年第8期70-73,共4页Health Medicine Research and Practice

基　　金：贵州省中医药管理局中医药、民族医药科学技术研究课题(QZYY-2019-063)。

摘　　要：目的 探讨Viabahn覆膜支架治疗下肢动脉硬化闭塞症的临床疗效,为下肢动脉硬化闭塞症腔内治疗提供新思路。方法 选取2020年1月—2021年9月天津港口医院诊治的102例下肢动脉硬化闭塞症患者为研究对象,采用随机数字表法分为对照组与观察组,每组51例。对照组患者采用裸支架治疗,观察组患者采用Viabahn覆膜支架治疗。比较2组患者临床手术指标、术后不同时间段血管畅通率、踝肱指数(ABI)、间歇性跛行距离、疼痛评分、并发症发生情况。结果 2组患者手术时间、术中出血量、术后下床时间比较,差异均无统计学意义(P>0.05);2组患者术后1个月、术后2个月血管畅通率比较,差异无统计学意义(P>0.05);观察组患者术后3个月、术后4个月血管畅通率均高于对照组,差异均有统计学意义(P<0.05)。2组患者术前及术后1个月ABI比较,差异无统计学意义(P>0.05);2组患者术后1个月ABI均大于术前,差异有统计学意义(P<0.05)。2组患者术后1个月间歇性跛行距离均大于术前,且观察组大于对照组,差异均有统计学意义(P<0.05)。2组患者术后24 h VAS评分均低于术前,且观察组低于对照组,差异均有统计学意义(P<0.05)。观察组患者并发症发生率为5.88%,低于对照组的19.61%,差异有统计学意义(χ2=4.320,P=0.038)。结论 Viabahn覆膜支架与裸支架治疗下肢动脉硬化闭塞症的短期疗效及血管畅通率无明显差异。但Viabahn覆膜支架可提高中远期血管畅通率,提高患者术后ABI、间歇性跛行距离,减轻患者疼痛且安全性较高。Objective To investigate the clinical efficacy of Viabahn stent graft in the treatment of lower limb arteriosclerosis obliterans,in order to provide new ideas for endovascular treatment of lower limb arteriosclerosis obliterans.Methods A total of 102 patients with lower limb arteriosclerosis obliterans diagnosed and treated in Tianjin Port Hospital from January 2020 to September 2021 were selected as the study subjects.Subjects were assigned to the control group and the observation group by the random number table,with 51 cases in each group.Patients in the control group received bare stents and patients in the observation group Viabahn stent grafts.The clinical operation indexes,vascular patency rate,ankle-brachial index(ABI),intermittent claudication distance,pain score and complications were compared between the two groups.Results There was no significant difference between the two groups in operation time,intraoperative blood loss and postoperative off-bed time(P>0.05).There was no significant difference between the two groups in vascular patency rate at 1 month and 2 months after operation(P>0.05).The vascular patency rate at 3 months and 4 months after operation in the observation group was higher than that in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in ABI before surgery and 1 month after surgery between the two groups(P>0.05).The ABI 1 month after surgery in both groups was greater than that before surgery,and the difference was statistically significant(P<0.05).The intermittent claudication distance 1 month after operation in both groups was greater than that before the operation,and the observation group was greater than the control group,with statistical significance(P<0.05).The VAS score at 24 h after operation in both groups was lower than that before the operation,and the observation group was lower than the control group,with statistical significance(P<0.05).The incidence rate of complications in the observation group was 5.88%

关 键 词：Viabahn覆膜支架 下肢 动脉硬化闭塞症 腔内治疗 

分 类 号：R654.4[医药卫生—外科学]